Plasma cells, also called plasma B cells, plasmocytes, and effector B cells, are white blood cells which produce large volumes of antibodies. They are transported by the blood plasma and the lymphatic system. Like all blood cells, plasma cells ultimately originate in the bone marrow; however, these cells leave the bone marrow as B cells, before terminal differentiation into plasma cells, normally in lymph nodes.
Development
After leaving the bone marrow, the B cell acts as an antigen presenting cell (APC) and internalizes offending antigens. That antigen is taken up by the B cell throug...