Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. There are various forms, and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity. Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium). == Types of toxicity == === Cardiovascular === General: diuretics, β-blockers, vasodilator agents Local: ACE inhibito...

John Hamilton McWhorter V (; born October 6, 1965) is an American linguist with a specialty in creole languages, sociolects, and Black English. He is currently an associate professor of linguistics at Columbia University, where he also teaches American studies and music history. He has authored a number of books on race relations and African-American culture, acting as political commentator especially in his New York Times newsletter. == Early life and education == McWhorter was born and raised in Philadelphia. His father, John Hamilton McWhorter IV (1927–1996), was a college administrator, and...

Noun: beau-catcher (plural beau-catchers)

1. (humorous, dated) A small flat curl worn on the temple by women.
2. Synonym: kiss curl

Noun: cowcatcher (plural cowcatchers)

1. (rail transport, principally US) The V-shaped device on the front of a locomotive (or other large vehicle) shaped so as to push objects on the tracks out of the way, to prevent major damage to the train.
2. Synonym: pilot
3. (radio, advertising) An advertisement at the start of a programme.
4. Coordinate term: hitchhiker

FidoNet is a worldwide computer network that is used for communication between bulletin board systems (BBSes). It uses a store-and-forward system to exchange private (email) and public (forum) messages between the BBSes in the network, as well as other files and protocols in some cases. The FidoNet system was based on several small interacting programs, only one of which needed to be ported to support other BBS software. FidoNet was one of the few networks that was supported by almost all BBS software, as well as a number of non-BBS online services. This modular construction also allowed FidoNet...

Miller's Crossing is a 1990 American neo-noir gangster film written, directed and produced by the Coen brothers and starring Gabriel Byrne, Marcia Gay Harden, John Turturro, Jon Polito, J. E. Freeman, and Albert Finney. The plot concerns a power struggle between two rival gangs and how the protagonist, Tom Reagan (Byrne), plays both sides against each other. In 2005, Time chose Miller's Crossing as one of the 100 greatest films made since the inception of the periodical. Time critic Richard Corliss called it a "noir with a touch so light, the film seems to float on the breeze like the frisbee of...