@Mitch There’s less than you may expect. “FDA history” is a search term that gets you their own take on it and that of Wikipedia. I haven’t seen any attempt to summarize state law. fda.gov/about-fda/fda-history
@RegDwigнt I have a lot of talent and I know it because I always work hard and am generally just a great guy. Can you teach me music? Like, not from the ground up, you literally have to dig the ground and put the foundations in
But I assure you that after you teach me everything, I will be very hardworking. 👍
The giraffe weevil (Trachelophorus giraffa) is a weevil endemic to Madagascar. It derives its name from an extended neck, much like that of a giraffe. The giraffe weevil is sexually dimorphic, with the neck of the male typically being 2 to 3 times the length of that of the female. Most of the body is black with distinctive red elytra covering the flying wings. The total body length of the males is just under an inch (2.5 cm), among the longest for any attelabid species. The extended neck is an adaptation that assists in nest building and fighting. To breed, females roll and secure a leaf of the...
The Myers–Briggs Type Indicator (MBTI) is an introspective self-report questionnaire indicating differing psychological preferences in how people perceive the world and make decisions. The test attempts to assign four categories: introversion or extraversion, sensing or intuition, thinking or feeling, judging or perceiving. One letter from each category is taken to produce a four-letter test result, like "INFJ" or "ENFP".
Most of the research supporting the MBTI's validity has been produced by the Center for Applications of Psychological Type, an organization run by the Myers-Briggs Foundation...
> Independent sources have called the test "little more than a Chinese fortune cookie",[5] "pretty much meaningless",[6] "one of the worst personality tests in existence,"[7] and "the fad that won't die".[8]
> In the U.S., more than one-fourth of the population has been fully vaccinated and supplies are so robust that some states are turning down shipments. The access gap is prompting calls for the U.S. to start shipping vaccine supplies to poorer countries.
This is good. India clearly needs all the vaccine it can get.
@CowperKettle A noble sentiment, but I can't imagine what kind of a movement would be needed to loose those shackles. It would likely involve death and mayhem on a scale unmatched even by the Taiping Rebellion.
@Cerberus I see lots of editorials to do so.. but I haven't heard of them doing it yet.
@CowperKettle As with any measure, it is oversimplified. So in its extremes it can be 'accurate' (eg if you score consistently in the 4 directions then it is somewhat predictive of other things. But unfortunately it is binary rather than continuous so there's little accounting for 'in the middle'.
Like BMI, if you're over 40 then it's highly correlated of problems (like hypertension, heart disease, type II diabetes. But body builders can also have high BMI (muscle mass giving them high weight). So you just have to be aware of extremes and context.
OCEAN (or Big 5 Personality traits is supposedly more scientific. It starts from Meyers Briggs (which was basically an educated guess by Jung) but then (however it was set up) used scientifically discovered dimensions of personality. Also it is continuous.
@Xanne Government intervention! Restricting freedoms!
1906? I didn't know they knew of the health problems of radioactivity by then. I thought it was only by the 30's that they realized.
@Xanne What? How dare you!
What gave you that impression? Did I do something to you?
@CowperKettle More grammatical: "There are fish in the river ..." Fish is singular and plural, but when used in the singular it requires an article: "There is a fish in the river ..." etc.
Certain animal names are used as singular and plural, without much rhyme or reason. For example, you can have 15 deer or 15 fish or 15 elk, but you have 15 monkeys or 15 turtles or 15 owls.
How many Putin's policemen does it take to arrest a single old lady..
In my city, an old woman was arrested in a similar manner for standing with a sign.
Meanwhile, the city is pockmarked with illegal parking lots where the mob forces people to pay for parking overnight, and the police does nothing. This is Putin's rule of law for you. This is "stability".
> In March, the United States, Britain and members of the European Union blocked a World Trade Organization proposal backed by roughly 80 nations, including India and South Africa, to waive patent protections for coronavirus vaccines.
> Overall, 77 million doses have been [exported] from the European Union since early December, 88 million will have been distributed internally by the end of the week, and 62 million shots have been administered within the bloc, European Commission President Ursula von der Leyen said.
While Europe has exported more than 20 million doses to Britain — no longer an E.U member — the bloc has so far sent fewer than 16 million doses to Germany, which is more populous.
Britain has exported no vaccine doses back to the European Union, according to E.U. officials.
Of those 77 million doses, I think I read 16 million had been sent to Covax, but I might misremember.
So I think the big vaccine exporters, India and Europe, are right to complain about the American export ban; but the destructive behaviour of Europe (and others) regarding patents is worse than an export ban, because no countries gain anything from that, it's just like...vandalism.
Or I suppose a few rich people at those pharmaceutical multinationals get even richer from this vandalism.
@Cerberus Intellectual property . . . not protecting it reduces its creation.
Anyway this idea that if you send us vaccine, we should send you vaccine is just weird. What makes this a reciprocal relationship? WHO seems tno do some good work but is heavily devoted to extracting from the rich to give to the poor and calling China poor.
It can be a means to that end, but an extremely inefficient means.
In most cases, it reduces innovation.
@Xanne One idea behind this is that total production is the most efficient if each manufacturer does what he does best.
So you could e.g. have some raw materials sent from China to Europe, where the vaccine is produced using some catalyst from America, and then it is bottled in India.
It is a national defense responsibility to protect supply chains, which many nations ignore. Then they cry over it when the gas pipelines get shut down.
“Europe” does not export anything. Governments regulate, interfere, prevent fulfillment of contracts, embargo, whatever. They can make contracts for delivery. The EU was late to make contracts.
You don’t want to accept that sometimes the wonderful EU makes mistakes.
@Xanne Perhaps nobody has a complete picture yet. But it seems 77 vaccine doses have been exported from the EU (of which 21 million to Britain, and how many to Israel and America?), while only 66 million have been administered in the EU. And no vaccines have been allowed to be exported to the EU (all countries mentioned have export blocks, I believe, not only of vaccines but probably also of components). So perhaps you can understand why the EU is finally making a fist like the other blocs.
The US contracted with six firms to whether or not the vaccine was successful in May 2020. You have to filter or figure out what is anti-Trump vs. what is true. This is difficult, but media bias is not new.
@Cerberus The leader at the time is blamed for bad things. Covid bad -> Trump bad. But the news (usually) fails to mention that US vaccine production started and was aided under the T-man.
@Mitch The 1906 act is more concerned with fraud, cheating—with diluting the snake oil rather than whether it works. Like most controls, it’s interested in the protection of existing businesses (in this case farmers) than anything else. Maybe you teach math?
@Mitch Sure, but what are you saying? Nobody thinks America was sitting on its hands under Trump, at least not with respect to the preparation of vaccine production.
@CowperKettle at some point it's not Putin himself that is 'afraid'. But it is a whole set of people in government at high and low levels who feel like being bullies. That said, I figure the build up near Ukraine is all Putin.
Not deep math ML, closer to "here's a picture that's sorta like how it works, go figure out the single Python command that has all that under the hood" ML
@Xanne I explain what happens inside the black box using pictures and hand waving, then students are told to go use the black box in almost identical ways to all the other black boxes they're using.
eg "SVM is like putting a line between two sets of points so that it minimizes the distance of the nearest points to the line. Look up the docs for calling it but it's something like SVM(X, Y, some hyperparameters)" (pretty much the same for other methods).
@Xanne Failing memory tells me I've been face-to-face with a camel and the most striking thing is how ugly they are up close, like every face in the Star Wars cantina all mushed together, so ugly that if they had bad breath it'd probably make them more likeable.
@Xanne It -is- statistics (a kind of stats). Except people who label themselves ML tend to deny it or at least make a big deal out of listing the differences.
it's basically "regression that is not least squares that was invented by people outside of stats departments and has no theory to support its quality"
But...
the ML methods tend to outshine the basic stats methods
@Mitch I remember you said once the machine processes given data but not new data, which surprised me. That’s why an algorithm developed to select programmers rejected women per se and had to be junked.
@Cerberus map of Netherlands at 1st century AD (left) and 10th c (right). sea level rising, but also identifiable cities.
@Xanne 1) most methods nowadays are still 'give it a single data set all at once and compute the model (the line that fits it)'. There are some methods that are 'incremental' (one instance at a time, but those aren't that common.
2) I think the reason behind the 'favoring dudes over dudettes' thing was due to sampling bias (also called selection bias), that the sample of programmers used for training was highly skewed male (because the population is highly skewed that way (hm, so maybe it is called 'population bias' or 'historical bias', and the model 'learned' that maleness was a predictor of quality). I don't know if the population has changed much since then (past ten years?).
So the fix would be to be more balanced in the sample in case the population hasn't changed (if the population is changing then yes certainly having an 'on-line' algorithm would help with a stale model.
@Mitch Yes, I'm not so sure it was the sea rising at that moment: the sea had risen earlier, and it was still busy pounding away all the land that it claimed for itself.
There was a large breach of the sea into the the Almere (the large semi-closed lake in the middle of the map) in the 11th century which accelerated things.
But by then engineering has progressed enough to keep most of the land, and in the 13th century large areas were reclaimed, I believe.
@Cerberus what would be an idiomatic way of saying in Dutch, "Dutch lyrics by X"?
Right now I have "Nederlandse tekst van Arie Van Der Ent".
I'm not sure about the preposition, and I'm not sure about the rest.
Thanks.
(Doesn't have to be "lyrics", can be "translation".)
@M.A.R. I can teach you anything at all that I'm better at than yourself, but I'm finding this Internet thingie exceptionally useless for that purpose.
Music in particular is a very hands-on thing.
One hour with a meh teacher sitting next to you may well teach you more than two months' worth of chatting with Daniel Barenboim.
@RegDwigнt Sounds OK. Tekst is commonly used with song texts. In case there might be confusion as to whether it is about the text of a song or something else, you could use liedtekst. For operas you would probably use libretto.
The praeposition van suggests origin. The praeposition door would suggest an effort was made to produce the text, because it emphasises the action of writing.
For the translation of a book, your would certainly use door.
If you received the text from Arie, and you're not sure who wrote it, or it doesn't matter, then use van.
@Cerberus Thanks–it didn't seem like such a thing existed but I figured I'd check. It's interesting if people are willing to review code for free but not English writing.
@Cerberus I'm not a skilled enough writer for my opinion to be worth much, but I'd guess that it could work effectively for a certain scope. Reviewing beginner to intermediate writing (thinking of ESL folks) of limited length probably involves fairly common objective errors.
Sometimes the code review post will ask why something doesn't work but often it will be that they implemented something in a way where the design could be improved. There's a lack of abstractions. Or they aren't familiar with certain language features. There's a lot of overlap with aspects of writing skills.
@Mitch well, the 1960s things were Amendments, so that should actually suffice for a reason. I googled, and apparently, before that, if the FDA didn't disapprove of a drug in six months, it automatically gained approval
With today's scale, that's a ridiculously short amount of time. Drug development takes more than a decade usually