Several. It is mainly the Monte Carlo by Rob Leuschke and the Slavkappen. The Slavkappen is in my opinion a very good font, but the long s is just wrong. From what I got so far.
1. It is better to edit the font than to fix it on LaTeX-level.
2. The fd-file tells pdfLaTeX, what to use from the font. It is not necessary by LuaTeX, but usable by it
3. For Monte Carlo it makes only sense create an fd-file to make the private area in the utf coding accessible. But in doubt, better stick to Lua(La)TeX.