VSC may refer to:
== Organizations ==
Venezuela Solidarity Campaign, a British political group
Vermont State Colleges, the U.S. state of Vermont's system of public colleges
Vietnam Solidarity Campaign, a Vietnam War-era activist group
Volunteer Special Constabulary, a component of the Singapore Police Force
Video Standards Council, of the United Kingdom responsible for promoting standards in the video industry
Volunteer Service Corp, at Wake Forest University
== Places ==
Valley Stream Central High School, in Valley Stream, NY, US
Vermont Studio Center, a fine arts and writing residency program...