@NathanMerrill ignore the first, jump over the second. You can ignite the third, because it'll rise slightly off the ground. Alternatively, dash over it (without landing your jump) which helps to get into range for two nail hits.
@NathanMerrill I used to do it all the time and it seemed very reliable, but dashing over the fourth one is even safer and has the benefit of getting more damage in, so maybe try that. You can probably see how I do it in my PoH run