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00:01
He's talking about the AI BS propagated by tech companies.
As AI being the new tech flavor of the month.
00:17
So far I'm underwhelmed by the Bing chatbot.
> Let's learn together. Bing is powered by AI, so surprises and mistakes are possible. Make sure to check the facts, and share feedback so we can learn and improve!
They are making "surprises and mistakes" sound like a feature of AI.
And I just can't wait to help Microsoft improve another product!
00:42
Hurray, we finally get to give new names to all those wicked states named for foreign despotic slavers and their kin! Henceforth, Virginia will be known as the great state of Chickahominy, Georgia will be known as the great state of Apalachicola, North Carolina will be known as the great state of Cherokia, Maryland will be known as the great state of Accohannock, and South Carolina will be known as the great state of Catawba.
And all $1 bills and $20 bills must be burned.
Also $2 bills.
Quarters must be converted to $1 bills, then burned.
It is by damnatio memoriae alone that our nation can be purified of its sins.
The state of Washington will be henceforth known as Nooksack.
Bonfires we need, and bonfires we'll get.
00:57
Bonfires of the inanities.
It's because of the report of a ʙʟᴀᴄᴋ Woman† who said she was traumatized when she learned that the National Audubon Society refused to cast off the name of evil from its organization. Let her who is without unburnt $1 and $2 and $20 bills in her purse toss the first torch upon the pyre!
With so many crosses to die upon, how to choose?
They've decided to rename Squaw Mountain in Colorado to Mestaa’ėhehe Mountain. Our gay governor was completely torched when he complained that the new name was too hard to type and harder still to say. This is what happens when somebody wants another slur tossed on the fire.
We can't type it and we can't say it. Who cares?
Wait till you see the IPA for this. You'll never believe it.
Hint: don't just say what you see. That's completely wrong.
It's a new shibboleth. If you can't say it right, you'll get tossed on the same pyre.
I assume you all know about the Skwxwú7mesh controversy.
01:22
Turns out I listened to this song in the spring of 1994.
I never knew the title, nor when it was recorded. A girlfriend gave me the cassette as a gift. I liked this song, although I did not understand much.
1825 slang dictionary: books.google.com/…
Apparently "a baker's dozen" once meant 14??
We have to change the original spelling because it has a taboo slur in in, so we will now be using Skwxwú7mesh. I'm sorry if you have no idea how that's to be pronounced.
The Squamish people (Squamish: Skwxwú7mesh listen, historically transliterated as Sko-ko-mish) are an indigenous people of the Pacific Northwest Coast. Archaeological evidence shows they have lived in the area for more than a thousand years. In 2012, there was population of 3,893 band members registered with the Squamish Nation. Their language is the Squamish language or Sḵwx̱wú7mesh snichim, considered a part of the Coast Salish languages, and is categorized as nearly extinct with just 10 fluent speakers as of 2010. The traditional territory is in the area now in southwestern British Columbia...
The word is Mestaa’ėhehe is in the Cheyenne Tsėhesenėstsestotse language, pronounced [tse̥hésene̥stsesto̥tse].
> Of whining suppliant and rampant fool,
Churls of an hour, unwhipp'd at school
> The phoneme /h/ is realized as [s] in the environment between /e/ and /t/ (h > s / e _ t). /h/ is realized as [ʃ] between [e] and [k] (h > ʃ / e _ k) i.e. /nahtóna/ nȧhtona – 'alien', /nehtóna/ nėstona – 'your daughter', /hehke/ heške – 'his mother'.
> The digraph ⟨ts⟩ represents assibilated /t/; a phonological rule of Cheyenne is that underlying /t/ becomes affricated before an /e/ (t > ts/_e). Therefore, "ts" is not a separate phoneme, but an allophone of /t/. The sound [x] is not a phoneme, but derives from other phonemes, including /ʃ/ (when /ʃ/ precedes or follows a non-front vowel, /a/ or /o/), and the past tense morpheme /h/ which is pronounced [x] when it precedes a morpheme which starts with /h/.
I thought it was a poetic quotation from somewhere.
01:32
@CowperKettle More Papacist heresies, I see. Nice!
Word of the day: concione
I never heard of this word before. books.google.com/…
Noun: concione f (plural concioni)
  1. (literary, archaic) assembly
  2. Synonyms: adunanza, assemblea
  3. (literary, now chiefly ironic) a solemn speech, harangue, tirade, diatribe
  4. Synonym: arringa
  5. (historical, Ancient Rome) an assembly of the people, summoned by a magistrate or a priest
  6. (historical, Middle Ages) parliament
@CowperKettle In what language?
In Italian, in Latin, in English, or in Russian?
> where the solemn concione would fail
Oh.
01:39
You know shit's gonna get real once they doff their fancy coats.
Yup.
 
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1 hour later…
03:50
> Neil deGrasse Tyson:

“In 2002, having spent more than three years in one residence for the first time in my life, I got called for jury duty. I show up on time, ready to serve. When we get to the voir dire, the lawyer says to me, “I see you’re an astrophysicist. What’s that?” I answer, “Astrophysics is the laws of physics, applied to the universe—the Big Bang, black holes, that sort of thing.” Then he asks, “What do you teach at Princeton?” and I say, “I teach a class on the evaluation of evidence and the relative unreliability of eyewitness testimony.” Five minutes later, I’m on the str
@Robusto Profesionals or natives also make that mistake?
@Vikas Or we type someone when we're meaning somewhat, or vice versa. They sound so close except for the very end and even then the point of articulation is the same, and our own fingers get of ourselves and "auto-complete" super-common words like these.
That is: [ˈsəmwən] vs [ˈsəmwət], or for some folks [ˈsʌmwʌn] vs [ˈsʌmwʌt] / [ˈsʌmhwʌt] (occasionally written [ˈsʌmwʌn] vs [ˈsʌmʍʌt]).
04:06
@tchrist I don't really understand what's happening here.
Why and how can someone be rejected as a juror?
@Cerberus Whenever the person — whether prosecutor or defending attorney — who is testing a prospective juror for suitability either for or against their position thinks that juror holds views that might make them hard to bamboozle into agreeing with the person putting them to the test. It's nucking futz.
So someone who acknowledges that a single eyewitness can't be trusted because all humans are fallible even when honest and so you need confirmation through multiple sources would drive them crazy.
@tchrist So the parties to the case can reject jurors?
Yes!!!
How odd.
That's one word for it.
04:14
We do not have juries, but I'd rather expect maybe judges to do this rejection of unsuitable jurors?
The whole way voir dire and peremptory challenges work in jury trials is really confusing for those of us outside the legal professions.
Voir dire is trying to figure out whether you have a competent and impartial juror. In theory. In practice, it's used for a great deal of bullshit.
Voir dire (; often ; from an Anglo-Norman phrase meaning "to speak the truth") is a legal phrase for a variety of procedures connected with jury trials. It originally referred to an oath taken by jurors to tell the truth (Latin: verum dicere). This term is also used informally to describe the practice of jury selection in certain jurisdictions.The term "voir dire" comes from the Anglo-Norman language, with "voir" deriving from Latin verum, meaning "[that which is] true." The phrase has historically been used in legal contexts, particularly in relation to jury selection and determining the a...
> In the United States, voir dire is the process of questioning prospective jurors about their backgrounds and potential biases, as well as examining the qualifications of expert witnesses. The process of jury selection and managing voir dire is a crucial area of study for criminal trial attorneys, with organizations such as the Center for Jury Studies and the American Bar Association conducting research on the subject.
Unusual.
> In the United States, voir dire is the process by which prospective jurors are questioned about their backgrounds and potential biases before being chosen to sit on a jury. "Voir Dire is the process by which attorneys select, or perhaps more appropriately reject, certain jurors to hear a case."[16] It also refers to the process by which expert witnesses are questioned about their backgrounds and qualifications before being allowed to present their opinion testimony in court. As noted above, in the United States (especially in practice under the Federal Rules of Evidence), voir dire can al
Strike for cause (also referred to as challenge for cause or removal for cause) is a method of eliminating potential members from a jury panel in the United States. During the jury selection process, after voir dire, opposing attorneys may request removal of any juror who does not appear capable of rendering a fair and impartial verdict, in either determining guilt or innocence and/or a suitable punishment. An example would be a potential juror in a murder case, where the sentencing options include the death penalty and a lesser sentence (such as life without parole), who states that they "would...
In American and Australian law, the right of peremptory challenge is a right in jury selection for the attorneys to reject a certain number of potential jurors without stating a reason. Other potential jurors may be challenged for cause, i.e. by giving a good reason why they might be unable to reach a fair verdict, but the challenge will be considered by the presiding judge and may be denied. A peremptory challenge can be a major part of voir dire. A peremptory challenge also allows attorneys to veto a potential juror on a "hunch". The idea behind peremptory challenges is that if both parties have...
You don't have to give a reason.
> Controversy

The use of peremptory challenges is controversial as some feel it has been used to undermine the balanced representation on a jury which would occur using random selection. While courts are not allowed to strike out entire groups of people from a particular jury, some would argue that peremptory challenges give individual parties this power (Yeazell 624). This reach of power has allowed, and still can allow, attorneys to simply strike out groups of people, even if just on a whim (e.g. all football fans may be struck from the jury).[1] In the criminal case Batson v. Kentucky,
THIS is a large part of why you get, for example, all-white-male juries against for example black-women defendants. It's a mockery of "jury of one's peers".
The goal is to get a jury you can manipulate. Nothing else.
A moderately sophisticated prospective criminal juror who doesn't want to serve can nearly always say something during voir dire to get themselves dismissed so they don't have to sit there.
@tchrist Why all white male and not all black female?
If both parties do the same thing, why does one 'win'?
Numbers.
You interview 60 random jurors from the community at large. You have 30 peremptory challenges allowing you to veto someone without giving a reason. Only 20 of the 60 are black, so you veto all of them and still have 10 more you can boot.
That's a made-up example, but it shows one of the flaws of the system.
Canada fixed this.
> Canada

The rules regarding peremptory challenges in Canada were laid out in §634 of the Criminal Code of Canada. The number of challenges awarded to each of the prosecutor and the defense depended on the type of charge and maximum potential sentence. Twenty challenges were awarded in cases for high treason and first degree murder, twelve challenges for offenses with a maximum penalty greater than five years, and four challenges for jury eligible offenses with a penalty of five years or less;[3] In cases where the judge orders thirteen or fourteen jurors instead of the usual twelve, both
Late in 2019.
It's just a terrible system.
In my never so humble opinion.
It has been used for gross injustice, and not only in the slaver south, either.
Witches!
04:49
> Liverpool, May 1966, by Barry Feinstein.
Same kids, decades after.
@tchrist Ah, right, if you can reject so many.
06:16
@tchrist Interesting phrase, voir dire, never heard it before. Added it to Anki.
Good day, Xanne!
07:10
Wordle 656 3/6

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Yes, a good day!
08:01
@jlliagre but is that a reasonable comparison? Macron is not going to be reelected, so he can do some unpopular (but arguably inevitable?) stuff. He wouldn't have done so if he was a future candidate.
@tchrist these guys loved the sounds of old Volkswagen cars working didn't they?
 
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09:14
Colder, but sunny and snowless
09:50
Adding machine by Johann Helfrich von Müller, 1784
Johann Helfrich von Müller (January 16, 1746 in Kleve – 1830) was an engineer in the Hessian army who conceived the difference engine in 1786 (first written reference to the basic principles of a difference machine is dated to 1784), an idea that later evolved into modern computers. In 1784, he was responsible for an improved adding machine based on principles of Leibniz's stepped reckoner. Müller was demonstrably the first who came up with the idea of calculating mathematical tables automatically by a machine. To achieve this, he planned building a printing differential engine. However, this plan...
 
2 hours later…
12:04
@Vikas Not that one in particular, but ones like it.
Not that when in particular, but whens like it!
When and when is too . . .
#Worldle #440 1/6 (100%)
🟩🟩🟩🟩🟩🎉
⭐⭐⭐🪙
https://worldle.teuteuf.fr
#Worldle #440 1/6 (100%)
🟩🟩🟩🟩🟩🎉
⭐⭐⭐🪙
https://worldle.teuteuf.fr
Wordle 656 4/6

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12:40
One did you see a when-eyed man first?
12:53
> This is the only known photograph of an African American Union soldier with his family. Identified as Sgt. Samuel Smith of the 119th USCT, with his wife Mollie, and his daughters Mary and Maggie. en.wikipedia.org/wiki/…
They look so cool.
The ambrotype (from Ancient Greek: ἀμβροτός — “immortal”, and τύπος — “impression”) also known as a collodion positive in the UK, is a positive photograph on glass made by a variant of the wet plate collodion process. Like a print on paper, it is viewed by reflected light. Like the daguerreotype, which it replaced, and like the prints produced by a Polaroid camera, each is a unique original that could only be duplicated by using a camera to copy it. The ambrotype was introduced in the 1850s. During the 1860s it was superseded by the tintype, a similar photograph on thin black-lacquered iron, hard...
Daily Quordle 437
4️⃣9️⃣
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m-w.com/games/quordle
I saw a black student today, sitting in a bus that rode side by side with the bus I was on.
I wanted to take a photo of him, but felt too shy.
Black people are rare here.
Word of the day: End of Greatness (The End of Greatness is an observational scale discovered at roughly 100 Mpc (roughly 300 million light-years) where the lumpiness seen in the large-scale structure of the universe is homogenized and isotropized in accordance with the Cosmological Principle)
@CowperKettle Yeah, probably the last thing that guy wants is people taking pictures of the novelty. But I could be wrong.
My sister said that people were staring at her in India, because she was white.
When I was in my 20s a friend of mine, of a similar age, was this statuesque woman over 180 cm tall with flaming orange hair. When she went to study in Tokyo, she said, she would stop traffic just by walking down the street.
13:04
Great. My friend went to Japan several times, to live in Japanese families and learn the culture. But she is short, maybe 160 cm, and with black hair.
A vomitorium is a passage situated below or behind a tier of seats in an amphitheatre or a stadium, through which big crowds can exit rapidly at the end of an event. They can also be pathways for actors to enter and leave stage. The Latin word vomitorium, plural vomitoria, derives from the verb vomō, vomere, "to spew forth". In ancient Roman architecture, vomitoria were designed to provide rapid egress for large crowds at amphitheatres and stadia, as they do in modern sports stadia and large theatres. == Modern examples == Smock Alley Theatre in Temple Bar Dublin has two vomitoria, one stage left...
Daily Octordle #437
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Score: 72
Daily Sequence Octordle #437
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Score: 70
13:49
> The coroner reported that no traces of illegal substances or alcohol were found in Smith's system at the time of his death but did find prescribed levels of antidepressant, anxiolytic, and ADHD medications, including clonazepam, mirtazapine, atomoxetine, and amphetamine.
Word of the day: polypharmacy
Steven Paul Smith (August 6, 1969 – October 21, 2003), known professionally as Elliott Smith, was an American musician and singer-songwriter. He was born in Omaha, Nebraska, raised primarily in Texas, and lived much of his life in Portland, Oregon, where he gained popularity. Smith's primary instrument was the guitar, though he also played piano, clarinet, bass guitar, drums, and harmonica. He had a distinctive vocal style, characterized by his "whispery, spiderweb-thin delivery", and often used multi-tracking to create vocal layers, textures, and harmonies. After playing in the rock band Heatmiser...
Whose picture is that on his shirt.
Maybe some musician? ..CEPHUS
Bocephus.
Randall Hank Williams (born May 26, 1949), known professionally as Hank Williams Jr. or Bocephus, is an American singer-songwriter and musician. His musical style is often considered a blend of southern rock, blues, and country. He is the son of country musician Hank Williams and the father of musicians Holly Williams and Hank Williams III. Williams began his career following in his famed father's footsteps, covering his father's songs and imitating his father's style. Williams' first television appearance was in a 1964 episode of ABC's The Jimmy Dean Show, in which at age fourteen he sang several...
14:18
@CowperKettle That's a weird graph to make (and sort of misleading). Most graphs like that are measuring performance, ie make a new machine and measure it and show that the measure is experimentally higher than ones that came before.
But this graph is showing what one hyperparameter has been chosen for the machine -before- any training happens. ie the y-axis is not measured after the fact but just what the builders decided was possible.
what the hyperparameter is is the length of the input sequences (for both calculation and for training). eg if all your input data is in terms of sentences, then the input length can be set at 64 tokens (expecting that almost entirely of your corpus the sentences will have 64 or fewer tokens (words) in them.
and if your sentences are less than length 64, then you pad out the length with null to make all inputs exactly 64 tokens in length (that's just a programming detail).
So if you are creating a language model for sentiment analysis of single sentences (classify a sentence as positive neutral or negative) then length 64 should be sufficient for highly accurate classification.
But usually more than one sentence together is the input situation, ie if you want a chat system, you may want your inputs to be the 10 most recent turns of the conversation.
powers of 2 are chosen because computers.
2048 = 2^11 was seen as a reasonable enough size of context that was also computationally feasible -and- gave good accuracy.
That graph looks like a PR stunt based on seeing that GPT-4 used a context (input) length of 32k (= 2^15). The engineers chose this because they want to allow -lots- of context, ie lots of prior text, in order to help predict/generate better following text.
You may have heard of 'prompt engineering'. That is the art of specially designing the 'prompt' that a person inputs into a chat system in order to get a more desirable output.
The 'prompt' is exactly the input. It is exactly the full context.
14:35
He's quite the accomplished entrepreneur.
It allows a user to say "I have a question about quantum thermodynamic cosmology, but I want you to answer in terms that a 13 year would understand. Also you can use emojis and fart jokes to explain. My question is "Can you use the difference in radius of the event horizon of a black hole and the rotational bulge of the mass as a wormhole?"
All that prior stuff is setting up the context. It can be very elaborate.
I'm pretty sure that ChatGPT and Bard and LLaMDA all have preset system prompts, ie for whatever you submit, it automatically prepends its system prompt for extra context (eg "Answer succinctly, don't answer about anything after (some date), some other very general restrictions")
Anyway, about the PR part. Someone probably saw "GPT-4 has 32k size input" and then looked at a handful of other recent models (cherry-picked them that is) that were 2k and decided to make a graph.
The thing that makes me say 'PR stunt" is that they use the term 'foundation model' which is purely a marketing term. It is intended to make you think that such a model is a reliable 'basis' for further applications.
All these models that have come out are not reliable in so many different ways 1) not reliable as to truth (it doesn't operate on truth values) 2) not reliable as to same output on repeated same input (it uses a random number generator to get some human sounding variation) 3) not reliable as to fixed model (they keep updating things in the background)
@Cerberus So my prompt needs a little more tweaking to order that burrito and get it delivered quickly.
@CowperKettle a little more... why didn't they use bigger contexts before? A bigger context needs more data to get the same level of accuracy (more instances (= more time) to train on to converge to same accuracy).
They (GPT-4 creators = OpenAI) probably collected a larger corpus (they are not very open, they haven't told people what is in their corpus (though we have a good idea)).
And they also probably used a larger farm of TPUs for computation.
14:57
Do Androids Dream of Electric Sheep? (retrospectively titled Blade Runner: Do Androids Dream of Electric Sheep? in some later printings) is a dystopian science fiction novel by American writer Philip K. Dick, first published in 1968. The novel is set in a post-apocalyptic San Francisco, where Earth's life has been greatly damaged by a nuclear global war, leaving most animal species endangered or extinct. The main plot follows Rick Deckard, a bounty hunter who has to "retire" (i.e. kill) six escaped Nexus-6 model androids, while a secondary plot follows John Isidore, a man of sub-par IQ who aids...
@Mitch Agreed. I might add 4: not reliable in basic logical reasoning.
in CONLOQVIVM, 21 hours ago, by Cerberus
> GPT: “Fortius” is the neuter form of the comparative adjective “fortior”, which means “stronger”. In this context, it is used to describe the bull. The neuter form is used because the gender of the noun “taurus” (bull) is masculine, and the adjective must agree in gender with the noun it modifies.
> The neuter form is used because the gender of the noun “taurus” (bull) is masculine
Yeah.
@Cerberus I subsume that under '1) not about facts'
Fake facts? How usual.
@Mitch OK I exsumed it.
Stop digging up the past.
15:05
You know me.
All too well, pal.
But... to be devil's advocate... it could be that people think of the whole thing as -approximate-. That is as long as it gets things right most of the time, that's OK. And statistically predicting words often gets logical inferences right because most writing has correct logical inferences and the LLM gets that pattern (not the -logical- pattern but the pattern of words that logical inferences tend to get)
and so if it works really well on short inferences... hey, that's good enough for figuring out whodunit in a 30 minute murder mystery
(but maybe not if you want to check the correctness of a VLSI chip like Pentium.)
And there's a lot of post pandemic devils out there just looking to make a buck or two on bit coin sheep.
@user2236 There is some concern with the crash of many bitcoin companies, that all the hypebros from that industry has moved over to AI.
Yup, looking to fleece the vaccinated new generation.
With a potential global nuclear war brewing in the Ukraine, organizations like QAnon are turning into cult followings.
15:16
@Mitch And perhaps a sufficiently enormous LLM thing will produce replies indistinguishable from an intelligent entity, ones that are correct and useful 99.9% of the time.
@Cerberus Maybe. There will need to be lots of experimentation on what the limits of what it can do (eg how many steps in a syllogism can be guaranteed reliable).
But the corpus any of these things can be trained on is not 'all human knowledge'.
Google very well may have access to all (digitized) books from the Stanford library. But there's a lot of human knowledge that is in non-public databases.
And also these LLMs only have access to blind text... there's no connection with physical reality (yes it has some pictures, that provides some physical relevance) but I mean being in a motivated body that is hungry in a family and needs a job etc.
text is just symbols and means nothing by itself. There is a lot of meaning in the structure but there is much much more that is not given by the structure.
Yeah, reading is complex.
@Cerberus Also 'intelligent' is doing a lot of work there. What you think of as intelligent has certain implications that are not the implications of what is possible for these LLMs (or machines not yet built).
15:32
What is the beginning of intelligence?
✔️
Without question.
@user2236 wait, QAnon is asking for Bitcoin? Who does the money go to?
Their Queen 👑
15:45
Liz is dead
Darth Vader.
Either god stopped blessing the queen, or god is also dead
Man, Covid has been hard
@user2236 They're turning into cult followings? What were they before that?
Cult droppings
No really, for a while all the rejects from the other cults seemed to fit in QAnon
Yeah, I find their beliefs unfathomable. How can someone be that stupid and gullible?
15:58
I remember when the Obama birther conspiracy was around the extreme conservatives here who hated Rouhani madeup this conspiracy theory that his real name is something else
That still gets me every time. "Rouhani" itself means "a spiritual man", a reverent way to refer to Mullahs. That the guy was a reformist and negotiating with filthy Americans, they had to feel like hating him somehow, and it was harder for them when he was called a name they had learned to respect since childhood
And I suppose that's mostly it for these people. They profile someone based on one thing, then form arguments from emotional conclusions.
Of course the arguments would be stupid
1. Everything is a conspiracy.
2. We define ourselves by what we hate, not what we love.
@user2236 Exactly.
Those two simple steps took Hitler to the top.
16:19
Probably a Zilog 8-bit CPU.
@Robusto Great for saving recipes!
@Mitch And little else.
@Mitch But you would have to print out the recipes if you had more than five or six.
@Robusto It's a start.
And it "grows with you."
All else that is needed is a rudimentary 3-D printer with the 'ink' being 'food' elements, and you can program it to make a ham sandwich.
It's kosher!
16:28
Does the printer chew its cud and have cloven hooves?
If not, better check with your rabbi.
@Robusto It doesn't need to. That's the beauty of it.
But if necessary it can print both those out.
But can it print money?
That's the million dollar question.
and can that money buy me love...
@user2236 But that's what I want.
Two opposing views of money by the Fab Four.
16:44
I think Floyd did the same...
... perhaps it was time.
 
2 hours later…
18:56
@Robusto someone should tell them growing hearts aren't a good thing. Or growing systems
19:14
Divorce rates are probably often higher in lower socioeconomic statuses, so yes, money can buy love.
 
1 hour later…
20:30
@M.A.R. My watch is about a million times more powerful than that "computer" in the ad.
@Robusto How many recipes do you have on that watch, huh? Ha got you there.
reads NYT Cooking article on watch
Never mind.
@M.A.R. Are you telling me that the heart of a baby is enough for when that baby grows up to be Andre the Giant?
20:45
@Mitch I don't cook very much.
@Robusto Install Microsoft Bing on it.
That would be a bit of a challenge.
21:40
@Mitch yes if you mean they're the same cells, no if you mean they're the same size. Once they fully differentiate into pacemaker, conducting and contracting cells (speaking about myocardium), they only get a little bigger to accomodate for body size, and even then they lag behind a little bit. It's not a conscious or controllable form of growth. 'A growing heart', on the other hand, does it at a much faster rate, and due to various reasons that have resulted from the (perceived)
. . . inadequacy to do its job. There are two major problems with big hearts, both pretty serious: 1) There is now less space in the ventricles, so the heart pumps less blood at every beat. Beyond a certain point, the organs will not be reperfused, and once we see the clinical signs of that, we call it 'heart failure'.
2) There are now bigger distances for the electrical impulse of the heart to travel. Beyond a certain point, the impulses would not have fully travelled all the myocardium before another is generated. Cells have a 'refractory period' after each stimulus when they can't be stimulated, but this will be overcome once the heart is big enough. What happens is a cell that had just expended a lot of energy to contract has to contract again, while some other cells don't, because they're still
. . . in their 'refractory period'. The result is some cells die, you can have a heart attack that way. And lethal arrhythmias are also very possible.
So the heart is the one muscle you shouldn't 'train'.
Thanks for listening. I hope you sleep better at night with this information.
22:44
@M.A.R. Granted, this is more of a pro- or anti-Macron poll in a turbulent time but it is still shocking that a majority of people say they would vote for a far-right candidate nationwide. Traditional political parties are increasingly overtaken by populist parties, whether on the right or the left.
@M.A.R. So are you saying that the heart (for mammals at least) doesn't grow new muscle cells after some time in infancy, and as the body grows through adulthood these existing cells only expand individually in size to get the result of a larger heart?
@M.A.R. clears throat
I tend to sleep just fine because I'll forget this conversation ever happened.
I mean not because of what we're talking about.
@Mitch yep.
My bedtime routine is: head hits pillow, starts thinking abou snore
wakes up, thinks about breakfast. The End
@M.A.R. Are other muscles like that?
only non-skeletal/smooth ones?
involuntary?
@Mitch Most (all?) skeletal muscles are like that
No one ever talks about diseases of the diaphragm
do people get diaphragm cancer?
22:55
Heart muscle is more like branched skeletal muscle than smooth muscle
@M.A.R. stops working out
starts working out so I can stop working out
There's some limited ability to repair, just like neurons. But just that limited ability
Liver tissue creates new cells right? And skin?
what about...bone? That's just for repair?
Liver tissue is epithelial cells, very relatively small number of smooth muscle
how about...
22:57
Epithelial cells are really good at cancer
well let me just ask are there any tissue types that grow new cells?
@Mitch What are you even wondering about at this point
@M.A.R. They mothers must be really proud of them.
So talented!
@Mitch Well of course, most tissue types do. Bones are dynamic. You constantly have bone tissue destroyed and formed in your body.
@M.A.R. I just sorta felt like ... new cells might be kind nice, to replace the old ratty ones. For whatever tissue.
22:59
Skin, the linings of the digestive, respiratory, and genitourinary tracts all consist at most parts of several layers of actively dividing cells replacing dead ones
hair
and toenails
but those aren't cells exactly
@M.A.R. whew
and that is why those in particular are conducive to more rapid cancer growth?
Neurons don't divide. Muscle cells don't divide. Reeeeally specialized cells don't divide (retina, nephrons, e.g.) And that's about it. Almost every other cell type divides, is destroyed, renewed, that sort of thing
But neurons don't really repair, right? But muscles cells do? how about retinal cells?
@Mitch Cells usually close off most of their DNA except the parts they need (genes to transcribe). DNA is very exposed and not closed off (methylated etc.) when dividing. So something mutagenic in the sausage you ate or coming from the sun is most likely to damage DNA then.
OK great. I think I'm ready for my board exams now.
Where's my scalpel?
Ouch! Oh. In my pocket!
23:04
Sorry, don't need any more doctors now. We have chatGPT
It will be included in your next delivered coronal mass ejection.
You really should cover your corona when you do that.
Sorry about my degrading your DNA.
@M.A.R. Even if we could trust ChatGPT with what it says, we don't know if there are medical textbooks in its corpus.
@Mitch "very limited ability to repair". Neurons cut from a specific part of their axon may grow that axon back (it's the long tube that sends the signal to the cell on the other end). A lot of the time chaos itself doesn't allow this to happen; damage to the spinal cord has lasting effects almost all of the time.
23:06
Habeas?
I mean if WebMD and blogs are its source for medical knowledge...
I'm taking back my scalpel
@tchrist Professor, you're ruining my GPA!
Muscle fibers (they're called that because they're very long cells) have these 'satellite' cells just in case of a necessary repair, but there's a limit to how much they can fix
@tchrist Yes I do, thank you very much!
@Mitch I don't doubt that it has recommended grounding or homeopathy to someone at this point
@M.A.R. grounding sort of works.
doesn't it?
23:10
Well if people wanna lie down they could just say that
@M.A.R. I'm pretty sure that would a little with HTN
a little?
temporarily?
Sep 11, 2014 at 14:48, by Mitch
OK a joke... Did you hear about the person taking homeopathy medicine?
Sep 11, 2014 at 14:49, by Mitch
They forgot to take their pill and died of an overdose.
@Mitch I think it's horseshit
Wait. Horseshit may have some useful bacteria
Coronal ejecta spiralling down into your spinning reference frame drag fictitious forces and coriolis effects that invisibly degrade the germ cells in your naked nipples. You may never give milk again.
@M.A.R. I thought there was some substantiated effect (related to any kind of meditation or relaxation attempt) ie that was not total horseshit
@M.A.R. It smells good.
From far away
@tchrist That took a turn
@Mitch There's probably half a dozen poorly designed experiments by 'scientists' that were already sure it has a benefit. You don't just tell people to lie down and then measure their cytokines. Where's your control? Where's your inducer group? Where's your damn theoretical framework?!
@tchrist Wasn't planning to.
Anyway we don't get much aurora here
23:17
They had some down to below 38 degrees here the other night.
Which I believe is where you are.
@M.A.R. Google is not being cooperative in contradicting you. This is going to be hard to reassess.
Especially since I can't ground my way out of it.
So they find some plant extract has phenols, tannins and flavonoids. They prove it's helpful and anti-inflammatory, yadda yadda. They add it to some sunblock and sell it to you at 60 times the price of a hydrocortisone cream. Doesn't make any darn sense!
@tchrist I chose the wrong night to stay up then
I was busy injecting rats with stuff that day and I was exhausted
@M.A.R. probably too much hyaluronic acid
23:20
Speaking of which, those cartoons lied to me. I think rats are way cuter than mice.
I slept through it as well. The pictures were impressive.
If we're lucky we'll get a nice new Carrington Event this cycle, at which point even Jamaica gets aurorae.
@tchrist I'm calmer now but not because of any science.
@Mitch If you want a moisturizer, you could achieve the same effect with petrolatum. Also like 1/100th of their price.
@M.A.R. Whenever I see a mouse I think "Wow, that's kinda weird looking, I was expecting more of a small cuter rat."
@Mitch Bene.
23:23
@M.A.R. And contributing to global warming. How about aloe?
If there's anything good about aloe, it is a really common crossword puzzle word.
If they stopped burning fossils I doubt they'd be warming much of anything. Aloe also works, but a bit more expensive.
No matter what they say about aloe vera, she's really not much use against a coronal mass ejection aimed right for your face.
The problem with petrolatum would be its oily texture. You don't like it when something can't easily be washed off.
tar
baby
Babies also have oily texture but may object to being used as moisturizers
23:27
The baby oil market seems profitable enough.
How many rolls of toilet paper does the average American go through per year?
Those are from exploited Third World babies that are paid 2 dollars a month for their oil.
Formula is expensive.
If we account for the legendary size of your toilets, it's probably 2.5x of what it should be
2
Thrice, say the shit-assed.
Thrice as great as it "should" be in European standards.
Because bidets.
Four and twenty rolls a year.
Two per month.
One person?
One household?
23:31
It has been asserted. I find it unlikely.
One person.
He must shit elsewhere a lot.
Whoa. Or woah.
We just wash our hands until we're sure we've contributed to the draught
> And no one buys more TP than Americans. The typical person in the United States uses about 24 rolls of toilet paper per year. That’s roughly three times more than Europeans — and among the highest per capita consumption of any country. Were the country to switch to bidets, millions of trees would likely remain standing every year.
If it takes a European six weeks to go through a roll of toilet paper, they sure aren't eating much.
You guys are known for homogeneity so no doubt all Americans can switch to bidets overnight
Even Iowa?
What will become of the corn cobs?
They'll have to find their mother
23:37
And do battle with Lazy Lob and Crazy Cob, and Attercop and Old Tomnoddy.
Attercop is what you give out to uniformed attaboys.
One thing I'll never get is people who keep pet spiders
The spider is not smart enough for a meaningful relationship (I think), and I think a fear of too many legs has been hardwired in our genes
@tchrist Uniformed is uninformed.

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