I'm hoping they'll go towards Firefinger and Kir Sabal first, then West towards the Oracle, then finally south towards Omu, but I could see a lot of different things happening. I'm planning to make some of the guides that want to go in that direction a bit more appealing.
especially ones they just met
Syndra shows up for all of the first 30 minutes of the campaign, and then players lose their biggest motivator to move quickly, unless I occasionally prompt them with her sending messages to them