\begin{tikzpicture}
\node[text width=70mm,inner sep=0pt] at (0,0)
{%
\mysize\itshape Location:\ Aud.~F (building 1534, room 125)%
};
\end{tikzpicture}
\begin{tikzpicture}
\node[text width=70mm,inner sep=0pt,font=\mysize\itshape] at (0,0)
{%
Location:\ Aud.~F (building 1534, room 125)%
};
\end{tikzpicture}