Let $M$ be an n-dimensional topological manifold. Then, a standard fact tells from algebraic topology states that for all $k>n$, $H^k(M,\mathbb{Z})=0$. UCT tells us (since $\mathbb{R}$ has characteristic $0$) that for all $k>n$, $H^k(M,\mathbb{R})\cong Hom(H_k(M),\mathbb{R})=0$.
Now assume a priori we did not know that $H^k(M)=0$ for all $k>n$, but we did know that for all $k>n$ $H^k(M,\mathbb{R})=0$. Could we use the latter fact to prove for all $k>n$ $H^k(M)=0$?