Nuking the integral as a kinda of "inverse" of the derivatives (except for a constant) means nuking the fundemental theorem of calculus. That will mean your integral will be something that is not lebniz integral nor a riemannian integral
(possibly not any type of integral with a known measure, (I am not very good a measures however)). I am not sure what happens when you do that, but that will surely be an interesting case given how most of out integrals rely on its relation with the derivative in order to be evaluated