$
\begin{bmatrix}
\frac{\partial u_1}{\partial x_1}&\frac{\partial u_1}{\partial x_2}&\frac{\partial u_1}{\partial x_3}&\frac{\partial u_1}{\partial x_4}\\
\frac{\partial u_2}{\partial x_1}&\frac{\partial u_2}{\partial x_2}&\frac{\partial u_2}{\partial x_3}&\frac{\partial u_2}{\partial x_4}\\
\frac{\partial u_3}{\partial x_1}&\frac{\partial u_3}{\partial x_2}&\frac{\partial u_3}{\partial x_3}&\frac{\partial u_3}{\partial x_4}\\
\frac{\partial u_4}{\partial x_1}&\frac{\partial u_4}{\partial x_2}&\frac{\partial u_4}{\partial x_3}&\frac{\partial u_4}{\partial x_4}