Well, I'm just copying and pasting the formal definition from wikipedia, because I've not yet studied this stuff extensively, but: "A topological space $X$ is called locally Euclidean if there is a non-negative integer $n$ such that every point in $X$ has a neighbourhood which is homeomorphic to the Euclidean space $E^n$ (or, equivalently, to the real n-space $\mathbb{R}^n$, or to some connected open subset of either of the two). A topological manifold is a locally Euclidean Hausdorff space."
Also, yes, $\mathbb{R}^n$ is a manifold.