Just put together a 67x36 CGoL Toffoli gate, which is highly suboptimal in terms of usability.
http://conwaylife.com/forums/viewtopic.php?f=&p=57193#p57193
Still, it's a lot more usable than calcyman's 40x42 one with Cordership inputs. For this new one, reasonable connections to other gates would only double the size, not increase it by three or four orders of magnitude.