> The enzyme α-AASA dehydrogenase (ATQ) oxidizes α-AASA to α-aminoadipic acid, and deficiency of this enzyme leads to accumulation in the body of harmful metabolites: pipecolic acid [2,23,24], α-AASA [2,25,26] and its cyclic equilibrium partner Δ1-piperideine-6-carboxylate (Δ1-P6C) [2,27], which inactivate pyridoxal phosphate (PLP)-the active form of vitamin B6.
I wonder - what is the meaning of cyclic equilibrium here?
> Considering the difficulty in precise quantification of a-AASA or P6C respectively due to the spontaneous equilibrium between them, it seemed that AASA-P6C might be the most reliable indicator in screening.
I was recently given the question:
The equilibrium constant, K, for the following reaction:
N₂(g) + O₂(g) ↔ 2NO(g)
is 4.00 x 10⁻² at a very high temperature. The reaction is at equilibrium at this temperature with [N2] = [O2] = 0.100 M and [NO] = 0.0200 M in a 2.00 liter flask. If 0.120 mol of N...
The Periodic Table
The Periodic Table