DE, de, or dE may refer to:
== Human names ==
De (surname), a Bengali family name
de, a nobiliary particle
== Places ==
Dé, Mali, a commune and town in Mali
De River, Mizoram, India
Germany (ISO 3166-1 alpha-2 country code)
.de, the ccTLD for Germany
Delaware (United States postal symbol)
DE postcode area, for Derby and surrounding areas in England
== Linguistics ==
De (Cyrillic) (Д, д), a letter in the Cyrillic script
German language (ISO 639-1 alpha-2 code)
De (kana) (で, デ), a Japanese hiragana/katakana
de-, an English prefix conveying negation
De/ye(뎌,여)- (also "Ne" or "ku'lhe"), ...