the easiest way to make colors more distinguishable:
- more saturated colors are better. the closer a color is to gray, the harder it is to pick out.
- larger regions of color are better. black text on red/green background is *much* easier to tell apart than red/green text on white background.
- when you're unsure, make it distinguishable in grayscale! if it's clearly different when you've changed it all to grayscale, anyone will be able to see the difference. so if you have both red and green, or both blue and purple, make one of them clearly darker