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A: Do African countries using Ivermectin have a better Covid-19 situation?

Mad ScientistThe first really important question is what exactly it means that those countries use ivermectin or are part of APOC. Both papers seem to assume that this status is binary, a country is either in the ivermectin/APOC group or not. But what exactly does this mean for the use of ivermectin in both g...

I think it boils down to how much, if any, ivermectin these and other countries are using right now. The 2015 date bothered me as well.
@user1721135 if you're after the evidence for Ivermectin alone, there's better sources. The paper that triggered the Ivermectin hype has since been retracted and was very likely fraudulent. There are simply no high quality studies that indicate that Ivermectin works at all against COVID.
The big paper, that was retracted, the one with the fake data, is definitely not what kicked of the hype and there are many more. "Success in the field" is a corner stone of the ivermectin argument, so it's worth looking into. Id love to see some real data on which country uses how much ivermectin, even if I just have to take their word for it, when it comes to cases. Case measuring is already not an exact science, not even in the western world. We don't have anything better unfortunately.
@user1721135 the only way to get a real answer are random controlled trials. And those don't show any effect so far when they're well done. Any other way of judging effectiveness of ivermectin has so many confounding factors to be essentially useless.
Covid is being treated with all kinds of things all over the world. The perfect trial is not the threshold for using a particular therapeutic.
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@user1721135 Randomized trials are not perfect, they are simply the best way to evaluate drugs. And so far they are inconclusive, there is no evidence Ivermectin works against COVID (cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2‌​/…). And a randomized controlled trial is exactly the proper threshold for widely using a particular therapeutic. They are required to approve any new drug.
Randomized trials are also not the threshold for using any particular therapeutic. Approving a new drug - yes, but this is not a new drug. Also ivermectin in particular has like 30 rcts showing benefits. There are some problems, but nothing in particular points to "not working", all the counter arguments boil down to "the data isn't perfect". its not perfect for other widely used drugs for covid either.
@user1721135 I linked a meta analysis that didn't show any good data on Ivermectin. There are certainly not 30 RCTs showing benefits. There is no evidence that Ivermectin works against COVID.
Yes there are, you just don't know about them because all you have read is this one study, that happens to exclude them.

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