GROMACS version:2022.02.22 GROMACS modification: Yes/No Here post your question Greetings Gromacs users, I have conducted 4.8us simulation, and I have obtained (single pdb) converged conformation of protein. I extended this replica simulation with mutations for about 1ns (trial) with box size 0.5 and 1nm respectively. My question is that whether, how to determine good box size…