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12:07 AM
@Mitch Valium is a BZD, I think.
 
> Vaciló y con esa voz llana, impersonal, a que solemos recurrir para confiar algo muy íntimo, dijo que para terminar el poema le era indispensable la casa, pues en un ángulo del sótano había un Aleph. Aclaró que un Aleph es uno de los puntos del espacio que contienen todos los puntos.
 
*Sigh* I should've learnt Spanish instead of French.
Mostly because SynthV supports Spanish but not French.
 
What rhymes with Aleph?
 
chef?
 
I should think so.
And Jeff.
But some people say it's stressed on the penult instead.
 
12:09 AM
Teff?
Teff (Amharic: ጤፍ), also known as Eragrostis tef, Williams lovegrass, or annual bunch grass, is an annual grass, a species of lovegrass native to the Horn of Africa, notably to both Eritrea and Ethiopia. It is cultivated for its edible seeds, also known as teff. Teff was one of the earliest plants domesticated. It is one of the most important staple crops in Ethiopia and Eritrea. == Description == Eragrostis tef is a self pollinated tetraploid annual cereal grass. Teff is a C4 plant, which allows it to more efficiently fix carbon in drought and high temperatures, and is an intermediate between...
 
I'll take an ale / if you have one.
And I'll have a nail / if you don't.
 
Aleph is the glottal stop, right?
 
No, it's an alpha. :)
I wonder if people say /ˈælɪf/.
It's also mathy.
Aleph (or alef or alif, transliterated ʾ) is the first letter of the Semitic abjads, including Phoenician ʾālep 𐤀, Hebrew ʾālef א, Aramaic ʾālap 𐡀, Syriac ʾālap̄ ܐ, Arabic ʾalif ا, and North Arabian 𐪑. It also appears as South Arabian 𐩱 and Ge'ez ʾälef አ. These letters are believed to have derived from an Egyptian hieroglyph depicting an ox's head to describe the initial sound of *ʾalp, the West Semitic word for ox (compare Biblical Hebrew אֶלֶף‎ ʾelef, "ox"). The Phoenician variant gave rise to the Greek alpha (Α), being re-interpreted to express not the glottal consonant but the accompanying...
 
@tchrist When I learned the Hebrew alphabet I always pronounced it that way. Of course I was about nine or ten, so ...
 
I've been pronouncing it [a lef].
 
12:13 AM
@DannyuNDos Stressed on which syllababble?
 
First
Or second-to-last.
 
Beth is easier. And not in the way you think.
 
> The Phoenician variant gave rise to the Greek alpha (Α), being re-interpreted to express not the glottal consonant but the accompanying vowel, and hence the Latin A and Cyrillic А.
 
@Robusto Are you in favor of GCH?
 
> In most Hebrew dialects as well as Syriac, the aleph is an absence of a true consonant, a glottal stop ([ʔ]), the sound found in the catch in uh-oh. In Arabic, the alif represents the glottal stop pronunciation when it is the initial letter of a word.
@DannyuNDos GVS? GSC?
 
12:15 AM
@DannyuNDos Do you mean that in a math sort of way?
 
Generalized Continuum Hypothesis
@Robusto Yeah.
 
Then I have no opinion.
 
Related fun fact: Under ZFC, aleph-omega is the smallest infinite cardinality that can be proven to be unequal to beth-one.
 
@DannyuNDos What does the G add?
 
Generalized.
 
12:18 AM
Was not the question.
 
The Continuum Hypothesis claims that aleph-one equals to beth-one. The Generalized Continuum Hypothesis adds that, for every ordinal O, aleph-O equals to beth-O.
 
@tchrist The continuum hypothesis is usually stated as the equality between the powerset of the naturals and the reals. The generalized version is basically the same, but for an arbitrary set and its powerset.
 
What does it mean to generalize the continuum hypothesis, is what I asked.
 
And personally, I'm in disfavor of CH.
 
@DannyuNDos Just to be contrarian?
 
12:20 AM
@XanderHenderson I only learned the CH, not the GCH. Only half educamated.
 
I mean, I'm open about thinking beth-1 = aleph-2, or beth-1 = aleph-3, and so on.
 
Personally I don't believe in any numbers greater than ten. If you can't count it on your fingers, it's not a number. Simple.
 
Meaninglylessly long ago it was.
 
@alphabet Nonsense. Anything bigger than three is fake news.
in Mathematics, Jun 23, 2018 at 20:31, by Xander Henderson
Personally, I am three-ist. I don't believe that there is any number larger than 3.
 
@XanderHenderson Three is the start of all the confusion. Back in the good old days there were one, two, and many, and that was good enough for us.
 
12:31 AM
@alphabet What about anything smaller than one?
 
1:00 AM
[ SmokeDetector | MS ] Bad keyword in answer (88): "There is a woman with a snapper."‭ by Nazari Roberto‭ on english.SE
 
@M.A.R. well, I actually wasn't looking for that word but now that I know it's the right one I'll use it.
@DannyuNDos I'll allow a half.
But one is not a number.
Things just are.
 
What about McDonald's Quarter Pounder Cheese?
 
1:31 AM
Is it good to load up on carbs after a long ride/work (30 km)? Or it's better to nibble on carbs during the ride, and after the ride have only a moderate amount of carbs, and a lot of protein?
 
1:42 AM
@CowperKettle Do you mean for building muscle mass? I've heard that there's basically no evidence that protein consumption improves that, contrary to popular belief.
 
@alphabet A U.S. Marine I knew said they were told to eat protein within an hour after exercise to build muscles. I can't vouch for that, but apparently the Marines do.
 
1:59 AM
@Robusto This meta-analysis suggests that my skepticism may be unjustified.
 
 
3 hours later…
 
1 hour later…
6:40 AM
@M.A.R. You mean using the word "crore" instead of million/billion? I think the reason is simple. We were taught only this in school. Most people wouldn't understand a number in million/billion. It's just like we use kilometers instead of miles. If you don't understand/agree with my explanation, you might be asking something different or more specific?
 
6:55 AM
@Robusto Yes, that's what we call addiction. It seems most players wanted #3 to be in Berlin. If you click the link under that picture, the legend is curious: grayscale photo of woman in black jacket and hat standing on sidewalk. That's not exactly what I see and it fails to mention that the newspaper on the top is the Völkischer Beobachter.
 
@alphabet Ah! I'm just being afraid of getting overweight, because I try to eat more since I've been riding 30 km/day
So I think that maybe I should switch to small bits during the ride
Maybe pack some dates into candy wrappers, and put some in my pockets to eat now and then.
@Robusto I recently read a study in which loading a lot of glycine post-exertion was somewhat good for restoring/synthesizing cartilage.
 
 
2 hours later…
8:56 AM
Swahili-derived word of the day: mazuku - a pocket of CO2-rich air that can be lethal to any human or animal life that gets enveloped in it.
>
Swahili for "evil wind", mazuku can be related to volcanic activity or to a natural disaster known as a limnic eruption. In the first case, noxious gases are released from the Earth's crust into the atmosphere, whereas in the second case the gases originate deep in a lake and boil rapidly to the surface.
 
 
3 hours later…
11:45 AM
> In southwestern Spain and Sardinia, the snakelocks anemone (Anemonia viridis) is consumed as a delicacy. The whole animal is marinated in vinegar, then coated in a batter similar to that used to make calamari, and deep-fried in olive oil
> This species is widely consumed in southwestern Spain, in the Gulf of Cádiz region, as otiguillas de mar (literally, "little sea nettles", because it has urticant properties before it is cooked), or simply ortiguillas. The whole animal is marinated in vinegar, coated in a tempura-like batter, and deep-fried in olive oil.
I didn't know we ate cnidarians!
Polypharmacy is unbounded.
Stop harming polyps and maybe they'll stop harming you.
"We'll be having Kenny Darling for dinner."

"You mean OVER for dinner?"

"No, I mean gnashing on deep-fried cnidarian."
Anemones are such a springtime thing.
 
@tchrist My mother used to cook anémones/orties de mer in omelettes.
 
@jlliagre Fascinating! Did you grow up near the sea?
 
@tchrist Definitely. Cassis then Ajaccio then Marseille.
 
Makes sense.
 
Cassis (French pronunciation: [kasi]; Occitan: Cassís) is a commune situated east of Marseille in the department of Bouches-du-Rhône in the Provence-Alpes-Côte d'Azur region, whose coastline is known in English as the French Riviera, in Southern France. It is a popular tourist destination, famous for its cliffs (falaises) and the sheltered inlets called calanques. The wines of Cassis are white and rosé, and not to be confused with crème de cassis, a specialty of Burgundy which takes its name from blackcurrants (cassis), not the commune. It is a filming location featured in The French Connection...
 
11:55 AM
> not to be confused with crème de cassis
 
#WhenTaken #59 (26.04.2024)

I scored 922/1000 🎉

1️⃣ 📍 43 km - 🗓️ 1 yrs - ⚡ 197 / 200
2️⃣ 📍 159 km - 🗓️ 0 yrs - ⚡ 194 / 200
3️⃣ 📍 109 km - 🗓️ 9 yrs - ⚡ 182 / 200
4️⃣ 📍 822 km - 🗓️ 1 yrs - ⚡ 174 / 200
5️⃣ 📍 291 km - 🗓️ 10 yrs - ⚡ 175 / 200

https://whentaken.com
 
@tchrist Qu'a vist Paris, se noun a vist Cassis, n'a rèn vist.
 
"Dialect" :)
 
#WhenTaken #59 (26.04.2024)

I scored 802/1000 🎉

1️⃣ 📍 68 km - 🗓️ 4 yrs - ⚡ 193 / 200
2️⃣ 📍 1002 km - 🗓️ 0 yrs - ⚡ 170 / 200
3️⃣ 📍 73 km - 🗓️ 14 yrs - ⚡ 169 / 200
4️⃣ 📍 3253 km - 🗓️ 11 yrs - ⚡ 119 / 200
5️⃣ 📍 1711 km - 🗓️ 5 yrs - ⚡ 151 / 200

https://whentaken.com
 
No wonder you're so sensitive to the southern accents and languages.
 
1:01 PM
@tchrist Is that... Borges?
@DannyuNDos um... OK... also quarters of any kind.
Wait...
maybe not quarter pounders... maybe there should be some dietary notice on those.
Also, really, a -quarter- pound? Maybe I've been in the US too long but that's not that much. Misleading by obscurity "It has a pound in it, must be big".
@tchrist I used to see a lot of medical records (no names!) and pretty much anybody who has a medical record has at least ten medications.
(of course, somebody who has a medical record is probably sick and so probably taking -something-, but in the other direction the medication list is usually monotonically increasing).
But anyway, shocking how many meds people take.
So many that it's very likely that some pair has a drug-to-drug interaction for which a doc may prescribe one -more- med to deal with the symptoms of the interaction.
Does that sound right @M.A.R.?
Maybe it's just an extra drug to deal with the side effects of just one of the meds.
But my story sounds more interesting because it sounds like the new drug to deal with one symptom might actually have in addition a -new- drug-to-drug interaction, needing another symptom 'management' drug... snowballing into a Sorceror's Apprentice multiplication of meds, an exponential acceleration of intervention that results in the patient exploding.
 
1:26 PM
Wordle 1,042 4/6

⬛⬛⬛⬛⬛
🟨⬛⬛🟩🟩
🟨⬛🟨🟩🟩
🟩🟩🟩🟩🟩
 
@Mitch It's not just the pairings. We simply have no data on n-way combinations, and never will.
@Mitch I know an old lady who swallowed a fly.
 
@CowperKettle OK that just sounds like a euphemism for farting.
 
@Mitch Sí.
 
@Mitch In German, words tend to stick together.
 
@tchrist With each new drug there are n-1 possible pair interactions, so the probability of another bad interaction goes up, at some point reaching a tipping point in a Malcom Gladwell fever dream of unsubstantiated metaphors.
 
1:32 PM
@Mitch +1
 
@Robusto Ionically? or covalently?
 
@Robusto German needs some lexical WD-40.
 
@XanderHenderson You'd have to ask them. I'm just an observer.
 
Which all the youtubes want to tell me is absolutely -not- for lubrication but for cleaning.
 
1:33 PM
@XanderHenderson I liked ironically better. ;--)
 
And all I can do is shpritz some more and I still can't unscrew it.
Ohhhh... you mean turn it the -other- direction?
Wow... so easy.
@Robusto That's iconic observation.
 
@Mitch The point is that it's not just a matter of how many possible 2-way combos there are in your set of N drugs. It's also how many 3-way combos, and 4-way combos, and 5-way combos, all the way up to N itself.
You just need the crustless version of pineapple-ham pizza. Problem solved.
 
Math is stealing our alphabet. And the Greek alphabet. What's next?
 
The ham is the crust.
 
@CowperKettle google translate just gives the translation of 'mazuku' as 'grants' as in multiple gifts of cash. But google gives all sorts of repeats of your quote.
GT is not that great with a lot of languages, but when you don't know, you don't know.
 
1:38 PM
@Robusto א
 
@tchrist What, they're stealing our chromosomes now too?
 
@tchrist OK that's nasty. The black olive has to go.
 
@Mitch What if they're blueberries?
 
@Robusto To be fair, modern mathematics was originally done in the Greek alphabet. The Latin alphabet is a bit of a newcomer.
 
@Robusto Math mostly stopped at aleph and beth. Only some weirdos went for gimel.
 
1:41 PM
@Mitch Gimme a daleth.
 
And the numbers are stolen from Islamic scholars, but they kind of appropriated Hindu numeration, so there's that, too.
 
@tchrist Holy singularity, Batman, that's exponential!
@Robusto Oh. Maybe it's just the black olives I don't care for. I should punish the pineapple for being next to the olive.
 
Next thing you know, we won't be able to do anything without math.
 
The ham is the pizza's crust. Now slather with pizza sauce and add cheese, onions, chiles, shrooms, kalamatas, and more cheese.
 
They look like prunes to me.
 
1:44 PM
@XanderHenderson In the original they didn't even have Greek. It was all counting on knuckles and elbows.
 
@XanderHenderson runs to the bathroom
 
Prunes are yummy!
 
How regular of you.
 
@Robusto Rah Rah Rah, gimme an Omega!
 
@Mitch No megas for you.
 
1:45 PM
@Mitch That's the last Greek letter you'll ever get from me.
 
@Robusto In all seriousness, the great majority of people can get by in their day-to-day lives without any math whatsoever... OK a little logic might help. Cetainly that was the situation for eons, but is still the case today.
 
@tchrist They have a tire purveyor called Big O. I wonder if it's related.
 
@tchrist low carb... nice
 
@Robusto What happened? Is your bathroom OK?
 
1:47 PM
@Mitch What? You mean I don't have to use calculus to figure out whether I can get across the street safely before I'm hit by oncoming cars? What is this magic?
 
@tchrist Oh, micron.
@tchrist I'm not sure that's as healthy as the label might lead you to believe.
 
@Mitch Take two ibuprofen and call me in the morning.
 
@Robusto I think 'the big O' refers to something else.
 
1:49 PM
@Mitch You're just a BigOt.
 
@Mitch What you don't like all the meat and cheese and salt?
 
@Robusto It's called 'survival of the luckiest'
 
Or is it the lye-processed former olives?
@Mitch Eat food. Not too much. Mostly plants.
 
@Robusto mmm
Bigos (Polish pronunciation: [ˈbʲiɡɔs] ; Ukrainian: бігус; Belarusian: бігас, bihas, or бігус, bihus, Lithuanian: bigusas), often translated into English as hunter's stew, is a Polish dish of chopped meat of various kinds stewed with sauerkraut, shredded fresh cabbage and spices. It is served hot and can be enriched with additional vegetables and wine. Originally from Poland, the dish also became traditional in the areas of the vast Polish–Lithuanian Commonwealth. == Etymology == The Polish word bigos is probably of German origin, but its exact etymology is disputed. According to the Poli...
@tchrist Au contraire. All that is too likeable.
 
@Mitch That's the part that's not so good for you. Don't eat more of it a day than you can fit on a flat tablespoon.
 
1:53 PM
À l'autre côté, we don't use Francophonies seldom enough.
@tchrist So what you're saying is eat one teaspoon of everything a day.
That's a lot of teaspoons to wash.
 
öf
 
> Some languages have additional oddities in the way they sort. Normally, all differences in sorting are assessed from the start to the end of the string. If all of the base letters are the same, the first accent difference determines the final order. In row 1 of Table 5, the first accent difference is on the o, so that is what determines the order. In some French dictionary ordering traditions, however, it is the last accent difference that determines the order, as shown in row 2.
 
OK French, you just -had- to do it your own way.
 
It's all because of how their inflectional morphology works.
 
2:01 PM
It's logical because they made a rule about it.
 
You kind of have to do it that way.
 
@tchrist Makes sense to me, especially as I pronounce cote like côte and coté like côté.
 
That's ridiculous. Next you're going to be telling me that all nouns have an additional unspoken random bit that tells you how to -sometimes- agree with adjectives and pronouns.
 
@Mitch Precisely.
 
OR that verbs conjugate person and number (I'll allow it for now) but often enough the pronunciations do not differ.
 
2:03 PM
Too.
 
OR that ... picks up a book of French and shakes it ... THIS.
To be fair, that's -all- languages except mine.
 
@Mitch WhataboutEnglish?
 
31 secs ago, by Mitch
To be fair, that's -all- languages except mine.
I mean other languages might complain about mine, but I don't really see it.
 
Hmm
 
Except 'kerfuffle'.
That really should be 'kerfluffle'.
It only makes sense.
D'un part, you can calm down but you can't calm up.
D'autre part, you can clam up but not clam down.
On the third hand you can come up -and- come down.
@jlliagre How do you say 'hmm' in French?
 
2:13 PM
Hmm
 
Is the 'h' silent?
 
Mmm
Hhh
 
hmm.
 
Not fully silent.
I need to wake down.
 
@Mitch How very simian of you! Only with opposable thumbs on your hind limbs as well, but you don't need those when you sport a prehensile tail. You can only have four hands xor a gripping tail as a primate.
 
2:31 PM
@Mitch conflates halluces and pollices
 
 
2 hours later…
4:19 PM
@Mitch Might be hum too. 'Hmm' is produced with a closed mouth, right?
 
4:57 PM
@jlliagre In English, 'hmm' is voiced nasal fricative, closed mouth. Also, the frication is through the nose. Timing-wise, the snorting happens before the voicing starts. So maybe it is two separate phonemes, one following the other.
 
5:09 PM
@Mitch Yes. In French, depending on the context and the way it is produced (length and tone), Hmm might mean 'yes', 'no', 'I'm not convinced', 'smells good', 'leave me alone' and others.
In particular, when repeated, the meaning differs between English and French. I was surprised when Americans first replied 'mm-hmm' to me because in French, that often means you do not believe that much what is said, unlike what I read here: used to indicate agreement, satisfaction, or encouragement to continue speaking.
 
> A month ago, Richard Slayman became the first living person to receive a kidney transplant from a gene-edited pig. Now, a team of researchers from NYU Langone Health reports that Lisa Pisano, a 54-year-old woman from New Jersey, has become the second. technologyreview.com/2024/04/24/1091734/…
> “There is a bright future in which all 100,000 patients on the kidney transplant wait list, and maybe even the 500,000 Americans on dialysis, are more routinely offered a pig kidney as one of their options”
 
@CowperKettle Less bright future for all these pigs though, but most are already doomed.
 
5:57 PM
@Mitch Been thinking about you.
0
A: Has British English always had two alternative pronunciations of "been"?

tchristWhat we say: Ben and bean, bin and bun Any of these enumerated below with numbered phonetics is possible in America, including from the same speaker depending on whether we’re talking a strong form or a weak form: [bɛn] [biːn] [bijn] [bijən] [bɪn] [bɨn] [bən] [bn̩] Strong forms: Ben and bean Wh...

It's hard to tell what the asker is asking. His title and his body are so different.
It's another non-native who doesn't understand that weak forms are normal.
Stress is a prominent feature of the English language, both at the level of the word (lexical stress) and at the level of the phrase or sentence (prosodic stress). Absence of stress on a syllable, or on a word in some cases, is frequently associated in English with vowel reduction – many such syllables are pronounced with a centralized vowel (schwa) or with certain other vowels that are described as being "reduced" (or sometimes with a syllabic consonant as the syllable nucleus rather than a vowel). Various phonological analyses exist for these phenomena. For example, in the following sentence...
And been is a function word, which means it gets mandatory weak forms.
So he thinks that there are "two" pronunciations.
That isn't what happens.
> Some monosyllabic English function words have a weak form with a reduced vowel, used when the word has no prosodic stress, and a phonemically distinct strong form with a full vowel, used when the word is stressed (and as the citation form or isolation form when a word is mentioned standing alone). In the case of many such words the strong form is also used when the word comes at the end of a sentence or phrase.

An example of such a word is the modal verb can. When appearing unstressed within a sentence and governing a verb (as in I can do it), the weak form /kən/ is used. However the str
Dnag, it's a duplicate.
Not only that, but individuals vary in how tense the vowel is, and how long it's held, often producing different pronunciations under different conditions (time of day, stress level, tiredness, irritation, etc.). So whatever it says in the dictionary, just treat that as a conductor's A; everybody varies from it in practice. — John Lawler Dec 19, 2017 at 15:59
 
 
1 hour later…
7:12 PM
Regardless of what happens in back-woods Appalachia et al, AmE just doesn't use bean. I have never heard it, except maybe in a song and I have heard a lot of AmE. Even the way some Pennsylvanians use "anymore" differently than other AmE speakers. I wonder if you haven't wandered off into being territory. — Lambie 1 hour ago
 
7:55 PM
@tchrist man, I can listen to those folk talk all day. Love that accent / dialect.
 
@tchrist it's actually probably a generous estimate. The rate is almost certainly significantly higher since people tend not to mention the herbal remedies or supplements they also take. It's much higher if you exclude people in their forties.
So yeah, taking 5+ drugs is called polypharmacy. Some of it is avoidable if your doctor is smart and makes smart prescribing choices, but really, there's no way for many people to avoid polypharmacy unless we find a lasting cure for hypertension and diabetes mellitus.
"Medication reconciliation" is one of the most important things a clinical pharmacist does. Anyway it's a good idea to take to any doctor or pharmacist a list of all the medications one is taking, a lot of the most egregious errors can be corrected that way.
For example, a cardiologist might have prescribed amlodipine + valsartan, and a nephrologist losartan for hypertension. The patient's not supposed to be taking both pills, and any doctor or pharmacist would correct that if they knew about it
 
@M.A.R. That's why you shouldn't go to different pharmacies for different drugs.
 
@Mitch there's not much wiggle room if the patient is diabetic, for example. Glucose control in DM requires at least one drug, often two or three. DM patients older than 40 yo require statins to prevent cardiovascular problems later on. DM will almost inveriably cause peripheral neuropathy in the legs, so you'd need to add at least one painkiller to the drugs.
In less lucky patients, DM will lead to eye problems, kidney problems, foot ulcers leading to infection (or even amputation) etc. Older patients develop hypertension a lot too, which will require at least one medication to manage.
A female elderly patient would almost definitely need calcium supplementation, or hormonal replacement therapy, to prevent osteoporosis.
How many drugs are we at? 12?
BUT thankfully, there's a lot of flexibility in avoiding prescription cascades (prescribing a drug just to cover up another one's side effect)
You can avoid having to prescribe gastroprotective drugs if you choose something besides losartan to control blood pressure, a drug that would not cause much stomach upset.
Taking prednisolone with milk or food could reduce the need for omeprazole or similar to prevent peptic ulcers.
Sometimes you have no choice though. Say, antiepileptic drugs (e.g. valproate) come with a bazillion horrible side effects, but one does not simply switch antiepileptic drugs, unless it's a really serious side effect (like hepatotoxicity)
So, all in all, any half-decent doctor could often easily avoid prescription cascades unless they're very callous
Questions like "can I not take this drug and live healthier instead?" are for those callous doctors.
About the dementia thing, it's all about what @Cowp mentioned earlier: Drugs that impact the cholinergic system in the brain can accelerate cognitive impairment.
 
8:26 PM
@M.A.R. It a country with only 30% of the people not being overweight, and with a third or more being obese, it's really hard to keep a lid on all that.
Oh and it was 42% two or three years ago. Sheesh.
 
That's a broader range of drugs than you would expect: Antipsychotics (that's their classification but they're prescribed for many other psychiatric illnesses too), antihistamines, some drugs used to control enlarged prostate symptoms, some drugs used to help quit street drugs, etc.
The reason is that a lot of these receptors on the brain look similar.
 
@M.A.R. What drugs do they prescribed for enlarged prostates?
 
Thankfully, it's the older drugs that cross the BBB significantly. These older drugs caused anticholinergic side effects, so these days we've mostly replaced them with drugs that don't cross BBB all that and should be safer.
 
@jlliagre There's a lot of room for sarcasm too, which may be more likely in the UK.
 
Diphenhydramine (Benadryl), quetiapine (Seroquel), and other 1st gen antihistamines are the most common significantly anticholinergic drugs we still use today.
 
8:33 PM
@M.A.R. Seroquel as cream is very different from oral route. :)
 
@jlliagre Everything but the squeal.
 
富士山 "Rich Samurai Mountain* (a/k/a Mt. Fuji)
 
But they're working on that.
@tchrist I don't know whether to be flattered or to console you.
 
@Robusto there are several classes of drugs for BPH, and the most modern anticholinergic is not worrying (solifenacin). The 1st choice drug is tamsulosin which is unrelated, it's an alpha blocker that relaxes the smooth muscle in prostate.
Tolterodine significantly reaches the brain, OTOH.
 
@tchrist The guy is new and he had a few first not so great questions (like the first few all negative voted). No big deal about being naive... if everyone knew everything there wouldn't be any reason to ask.
@tchrist voted to close as dupe
 
8:38 PM
@Mitch Thanks. Wish I'd noticed it before.
 
@tchrist who says it has to be unidirectional?
 
@M.A.R. Someone told me they were taking finasteride for that, and he said, "I can piss like I was 15."
 
@Robusto Even without enlargement you still will never piss like a racehorse again.
 
@tchrist Well, an old racehorse might need drugs for that too.
 
@tchrist That's why people go to different pharmacies for different drugs.
 
8:40 PM
15 is old for a racehorse, btw.
 
@Robusto tamsulosin is stronger and its effect more immediate, but it does not prevent BPH from getting worse. In individuals that meet certain criteria (e.g. high PSA), finasteride is a good option to prevent worsening of BPH, prostate cancer, and the like. Since it affects the androgenic hormones, however, its principal side effect (loss of libido) is less pleasant than tamsulosin (which is a minor headache caused by an eventual drop in blood pressure)
 
@M.A.R. At my age, loss of libido is inevitable. And not unwelcome.
 
That's what Plato said.
 
Those Greek dudes have said a lot of things
Maybe they had a Greek Language & Usage: Multi-Layered Discourse Room
 
When I think of all the things I could have done in my teens and twenties if I hadn't been slavering over the opposite sex ...
 
8:45 PM
Also, what's a libido? :( Did you know that it's feminine in Latin, not masculine?
 
@M.A.R. Oh? Any good examples?
"It's all Greek to me"?
I mean, in Greek of course.
 
Timeo Danaos et dona ferentes.
 
Tim Danos and Daisy Fuentes?
 
> Hi! I'm Tim Danos, your admissions representative at the University of Delaware.
The guy looks like me, NGL
Down to the forced smile at the camera
He looks shorter though
 
8:49 PM
@M.A.R. Probably said too many Greek things.
 
 
1 hour later…
9:58 PM
Wordle 1,042 5/6

🟨⬛🟨⬛⬛
⬛⬛⬛🟨🟩
⬛🟩🟩🟩🟩
⬛🟩🟩🟩🟩
🟩🟩🟩🟩🟩
Daily Octordle #823
6️⃣9️⃣
🕛3️⃣
🕚7️⃣
8️⃣🔟
Score: 66
Daily Sequence Octordle #823
5️⃣6️⃣
7️⃣9️⃣
🔟🕚
🕛🕐
Score: 73
 
10:14 PM
What's that word that means shit-talking a dialect you think you're better than?
 
10:25 PM
@tchrist Baragouiner?
 
@jlliagre No, not balbucir. :)
There's a term for dialect dissing. It's a form of bigotry.
Prestige thing.
> I sit beside the fire and think
of all that I have seen
of meadow-flowers and butterflies
in summers that have been;

Of yellow leaves and gossamer
in autumns that there were,
with morning mist and silver sun
and wind upon my hair.
@Mitch New question for ELU: “Have the Brits always rhymed think and butterflies?” :)
I'd quote it but then the children will be whining about were and hair rhyming. :(
> I sit beside the fire and think
of people long ago
and people who will see a world
that I shall never know.
That has haunted me every day of my life since first I read it.
> I sit beside the fire and think
of how the world will be
when winter comes without a spring
that I shall ever see.
That one.
 
@tchrist Not balbutier either :-) Baragouiner has nevertheless an interesting (probable) etymology. A rare French word from Breton 'bread and wine'.
 
10:55 PM
@jlliagre So the people on one side were offering guest rite by way of wine and bread, and the other thought they were babbling? :)
> Spring comes and goes and comes again
And all is nakedness and fen.
@Araucaria-Him I’d fain rhyme not fen with wain.
Nor again against the grain.
But these things change so quickly, it's a miracle we can still rhyme anything written in the 1900s.
 
@tchrist True
 
From cinders all gritty he's built us a city:
Old Christopher Wren has done it again.
I'm sure Wren couldn't have rhymed that one himself. :)
A marineer:
> The Wedding-Guest he beat his breast,
Yet he cannot choose but hear;
And thus spake on that ancient man,
The bright-eyed Mariner.
 
@alphabet Hey raccoon! You timed that there arrival just right. What's with the "place assimilation"? Are you trying to kid readers so that they go and speak to linguists and get misundertood or ridiculised? It's "assimilation of place". Right?
Huh?
 
11:11 PM
@Araucaria-Him I've fixed that typo.
 
@Araucaria-Him That would be Sir Bank Inksly.
Albeit nosso much in my own idiotlect.
 
@tchrist The other way around. The Breton travelers were asking to the innkeeper for some bread and wine an unintelligible way outside Brittany (bara gwin). Consequently, the Bretons were called Baragouins a derogatory way. Later the way they spoke was called baragouiner and that was no more directed to Bretons but any foreigner who spoke gibberish. That sounds like a popular etymology but linguists generally believe it's the most plausible.
 
@Araucaria-Him Actually, I was right the first time: some linguists do call it "nasal place assimilation."
 
@jlliagre Really? It definitely smacks of an À l’eau! C’est l’heure joke.
Babar no barbarian was.
 
11:18 PM
> These equal syllables alone require,
Tho' oft the ear the open vowels tire,
While expletives their feeble aid do join,
And ten low words oft creep in one dull line,
While they ring round the same unvaried chimes,
With sure returns of still expected rhymes.
 
Incidentally: that BrE/AmE difference in the strong form of been is on my list of differences between BrE and AmE that CGEL doesn't cover.
 
> Leave such to tune their own dull rhymes, and know
What's roundly smooth, or languishingly slow;
And praise the easy vigour of a line,
Where Denham's strength, and Waller's sweetness join.
True ease in writing comes from art, not chance,
As those move easiest who have learn'd to dance.
@Araucaria-Him I think His Papal Majesty is pulling our leg: he twice rhymed line and join. How did that work?
> Be thou the first true merit to befriend;
His praise is lost, who stays till all commend.
Short is the date, alas, of modern rhymes,
And 'tis but just to let 'em live betimes.
That one's ok. This next one? Not so much.
> No longer now that golden age appears,
When patriarch wits surviv'd a thousand years:
Now length of Fame (our second life) is lost,
And bare threescore is all ev'n that can boast;
Our sons their fathers' failing language see,
And such as Chaucer is, shall Dryden be.
Was boast bost or lost loast? Enquiring moinds want to know.
There's something about a man who responds to criticism with heroic couplets.
In three cantos, no less.
Yeah, his diphthongs are not mine.
> See, from each clime the learn'd their incense bring!
Hear, in all tongues consenting pæans ring!
In praise so just let ev'ry voice be join'd,
And fill the gen'ral chorus of mankind!
Hail, bards triumphant! born in happier days;
Immortal heirs of universal praise!
Mankoind?
Jined?
 
#WhenTaken #59 (26.04.2024)

I scored 822/1000 🎉

1️⃣ 📍 63 km - 🗓️ 3 yrs - ⚡ 194 / 200
2️⃣ 📍 4199 km - 🗓️ 14 yrs - ⚡ 101 / 200
3️⃣ 📍 128 km - 🗓️ 11 yrs - ⚡ 176 / 200
4️⃣ 📍 47.1 metres - 🗓️ 3 yrs - ⚡ 197 / 200
5️⃣ 📍 1567 km - 🗓️ 5 yrs - ⚡ 154 / 200

https://whentaken.com
 
11:36 PM
@alphabet Not really. That term's just about ok regarding cross-linguistic phenomena within the general scope of nasals, but hardly works for the language-specific dealveolar assimilation of /n/! (huff) And your hero would not approve. I bet you can't find him doing that anywhere!
@tchrist I don't know. I've been out-diphthonged.
 
@Araucaria-Him Fine, fine.
 
@alphabet There's a considerable amount of tongue-in-cheek there ;-)
@alphabet Ah, you sent that whilst I was trying to work out the proper hyphneatory form.
 
@Araucaria-Him "Cheek assimilation."
Is there an IPA symbol for tongue-in-cheek?
 
@alphabet Do I need to flag that? <--That's a joke!
 
@Araucaria-Him I know.
 
11:52 PM
@alphabet Don't think it's got any lingual-buccal approximates yet.
@alphabet Good!
Got to scram.
 
Of course, in raccoon linguistics we call them snoutal consonants.
 
#WhenTaken #59 (26.04.2024)

I scored 802/1000 🎉

1️⃣ 📍 68 km - 🗓️ 4 yrs - ⚡ 193 / 200
2️⃣ 📍 1002 km - 🗓️ 0 yrs - ⚡ 170 / 200
3️⃣ 📍 73 km - 🗓️ 14 yrs - ⚡ 169 / 200
4️⃣ 📍 3253 km - 🗓️ 11 yrs - ⚡ 119 / 200
5️⃣ 📍 1711 km - 🗓️ 5 yrs - ⚡ 151 / 200

whentaken.com
 
Huh.
> It’s somewhat unclear whether the book which eventually resulted – translated into English in the USA in 1967 – was intended as a sort of sophisticated in-joke among zoologists and perhaps scientists more widely, or created to be partly instructional, and to highlight the themes, terminology and theories of biology
 

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