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00:25
Hey, does someone knowshow to make banana bonds in ChemDRaw ?
 
1 hour later…
01:25
Off-topic?
0
Q: What is Shine-Dalgarno?

hthorntoI am trying to understand Shine-Dalgarno. I currently know it is related to ribosomal binding sites, it is only found in prokaryote cells and it is in front of the initial codon. Another question I had is how do you recognize that it is Shine-Dalgarno?

01:49
@Hexacoordinate-C At least in ChemDraw 12, there is the "Main toolbar", if this is set vertical, the second column, eigthth entry from the top will be "Drawing tools". Take the arc labelled by 90. Draw this once on the canvas; copy this one and rotate it for 180 degree; arrange the two to form a lentil-like shape.
Then, create two wedges, both for the left and the right, as if you were to draw propane. Tilt them with the 3D-lasso into perspective; and add H's and B's.
Eventually move the items into a reasonable ensemble, add the H's on the bananas -- if you intend to draw the 3centre-two electron bonds
Since these arcs are just a drawing without chemical meaning, ChemDraw may mark the atoms in question by red rectangles.
On the other hand, the arcs may be drawn more bold, and hence yield results like
@Buttonwood due to dns problems impossible to solve I can't see pictures in stack exchange websites
But thank you for your explainations. I got it ;)
Alternatively, scale the cyclopropane, and tweak the orientation of asymmetrically drawn p-orbitals (orbital tools), for example. Some prefer this way for banana.
Another question but about chemistry this time, I have troubles to understand this : pubs.acs.org/doi/abs/10.1021/ja408861p they give a mechanism (proposed) which involve a L-M-H molecule but I don't figure out which one it is
I don't see the link with the [Cu-Fe] catalyst
02:05
Cu is not even written in the scheme.
But looking at the abstract of the very article, Cu is present.
Do you understand which molecule is represented by LMH ?
It is bridging between the carbene, on the left hand side -- in the abstract's scheme -- towards the Fe; the latter in turn binds to two CO and cp.
Hence "L" is placeholder for /both/ Cu and the carbene.
I guess the scheme you uploaded was intentionally reduced, for clarity äll the rest on the left side was omitted.
Subsequently, the cycle looks very similar to the ones one draws for Pd chemistry, too.
oxidative insertion, reductive elimination, etc. pp.
OK so as I understand (sorry some english troubles too ^^) LMX represent the whole catalyst with and H more on the iron atom ?
Oh no
Hum well sorry but I don't understand what you said ^^
I can't see picture as I said ...
02:13
Oh, bummer.
I can send them but not see them lol
I made all tutorials i found on the web to roll it back but none of them worked
Yet, asked differently, do you have "some access"to the picture of the abstract?
It shows the two typical starting materials, the catalyst, and a representative product.
I can see all the picture in every website but not stackexchange lol
I see picture in the extract yes
Why why why why why why why whywhywhywhwyhwhy!?!?!?!? is this on HNQ?
2
Q: Explanation needed about aqueous solution

creekorfulWikipedia article claim that : An aqueous solution is a solution in which the solvent is water So basically, is writing $\ce{HCl(aq)}$ equals to : $\ce{HCl(l) + H2O(l)}$ ?

Returning to the cycle you cropped from the article,
02:16
@orthocresol Yes, should be on Bio.
initially the catalyst is represented as L-M-F-(CO)2cp.; left hand side, prior to (I).
Than the borane (on top of (I)) is performing the insertion.
Oh yes sure sorry lol ok I get it
3 am here
I prefer mechanisms when the catalyst is first in the top of the cycle :P
In such a way that the right-hand "rest" becomes the the carbene-bound-to-Cu-boundt-to-H; as one intermediate,
and the borane replaces the carbene.
Ok, reads like you got the thread to continue on your own.
Good luck and continuation. Bye.
Thank you @Buttonwood ! :)
@Loong It has to play some role in their research program. No fun in Germany, after all.
02:22
Et bien, c'était probablement un Francais ...
Ah tu es français ?
 
7 hours later…
09:42
@DHMO is this answer correct?
-2
A: Difference between Resonance Effect and Mesomeric Effect

JessicaThe difference is that resonance occurs mostly in closed systems (ring structures) while mesomeric effect occurs in open system ( long chains)

@Anonymous no idea
Anybody can verify/say about it?
 
2 hours later…
11:59
@Anonymous That's bullshit
Usually the votes should tell you that before I do
Don't take answers with a score of less than -1 seriously
That's your definition up there
 
5 hours later…
16:36
hellozzz guyz @Mithoron @Martin-マーチン
Anyone seen WildCat ?
@diffracteD Nah, he's busy these days
I wonder whether if referring to cats as 'he' is politically correct.
17:28
:D
well datz a strong point
maybe this will attract the cat
@pentavalentcarbon It looks fake :(
The cat is cunning
well it is a stock photo, but when I buy canned tuna fish it does look like that
@pentavalentcarbon I wonder what the fish is thinking when it sees the tuna
"Gee, is this how I end?"
Or "Father noooooooooooooo"
"wow, the back half of me is on the plate"
17:41
@pentavalentcarbon "I wondered what my butt looks like"
I think I'll have tuna fish for lunch now.
Meh, too salty
You have to get the kind with no salt added.
There are no such kinds of tunas here
!!flip
(ノ ̄◇ ̄)ノ~┻━┻/(×。×)
17:43
Unless you mean I make it myself
@pentavalentcarbon Autobot in a can
ohhhhhhhhhhh I get it
17:53
> The ability of small intestine cells to absorb nutrients and act as a barrier to pathogens is 'significantly decreased' after chronic exposure to nanoparticles of titanium dioxide, a common food additive found in everything from chewing gum to bread, according to new research.
> it can enter the digestive system through toothpastes, as titanium dioxide is used to create abrasion needed for cleaning. The oxide is also used in some chocolate to give it a smooth texture; in donuts to provide color; and in skimmed milks for a brighter, more opaque appearance which makes the milk more palatable.
> A 2012 Arizona State University study tested 89 common food products including gum, Twinkies, and mayonnaise and found that they all contained titanium dioxide.
@CowperKettle Bah, the media usually doesn't cover the greater stories
I'm skeptical of any 'here's something in your food. PANIC' articles
So much crap and misinformation about this out there . . .
the greater stories?
@CowperKettle The real stuff that happens in the scientific community usually doesn't make it to news
it's a scientific paper, published in a reviewed journal
> Zhongyuan Guo, Nicole J. Martucci, Fabiola Moreno-Olivas, Elad Tako, Gretchen J. Mahler. Titanium dioxide nanoparticle ingestion alters nutrient absorption in an in vitro model of the small intestine. NanoImpact, 2017; 5: 70 DOI: 10.1016/j.impact.2017.01.002
Because it's boring science, not panicky or futuristic or trivial
@CowperKettle Sure, but the claim ''it appears in all the food there is out there'' is misleading
17:58
Yes it does make it to news, but only on specialized sites like Science Daily
A lot of carcinogens are eaten everyday. The amount of ingestion is important
> Researchers have studied the effects of oral exposure to titanium dioxide, an additive (E171) commonly used in foodstuffs, especially confectionary. They have shown for the first time that E171 crosses the intestinal barrier in animals and reaches other parts of the body. Immune system disorders linked to the absorption of the nanoscale fraction of E171 particles were also observed.
> Sarah Bettini et al. Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon. Scientific Reports, 2017; 7: 40373 DOI: 10.1038/srep40373
18:22
@CowperKettle You should read the article first
@CowperKettle A lot of journal articles say something like ''it is possible that we may have found a possible potential connection between X and Y but further research may be potentially required about X's effects, Y, Z, N, M, some other letters and it may need to potentially be made clearer the possible link between the potential causes'' and the media goes crazy ''DEFINITE LINK BETWEEN AIDS AND AUTISM''
Hey @Gan
@M.A.R. 0.O
@Mithoron \o
@Mithoron The guy forgot to indent code correctly, and the code rendered
19:41
wow, why someone would make code rendering sth like that... nah maybe better not to know ;)
RIP Bill Paxton !!flip
(ノ ̄_ ̄)ノ\。:・゛。
20:03
@M.A.R. Oh, surprising :(
 
4 hours later…
23:41
hey @M.A.R. What's up?

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