I think I finally "get" the additivity theorem, using the following formulation:
Thm: If $F' \to F \to F''$ is an exact sequence of functors, then $|S_\bullet(F)| = |S_\bullet(F')| + |S_\bullet(F'')|$.
Proof: Geometric realization of a simplicial space forces locality with respect to $\Lambda^1[2] \to \Delta[2]$, i.e. it "makes composites unique". In particular, $F$ and $F' \oplus F''$ are identified. QED.
So in fact, additivity already holds when you localize $S_\bullet(C)$ to become a Segal space.
Thm: If $F' \to F \to F''$ is an exact sequence of functors, then $|S_\bullet(F)| = |S_\bullet(F')| + |S_\bullet(F'')|$.
Proof: Geometric realization of a simplicial space forces locality with respect to $\Lambda^1[2] \to \Delta[2]$, i.e. it "makes composites unique". In particular, $F$ and $F' \oplus F''$ are identified. QED.
So in fact, additivity already holds when you localize $S_\bullet(C)$ to become a Segal space.