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2:01 AM
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Q: Why is episodic use of infliximab associated with a higher incidence of antibody formation towards the drug?

KarlIt has been shown in many studies that episodic use of infliximab (and other Anti-TNF agents) increases the incidence of antibody formation towards the drug, when compared with giving the drug on a regular schedule, such as once every 8 weeks 1. Why is this? 1:Incidence and importance of antibo...

 
 
5 hours later…
6:36 AM
1
Q: Meaning of "central registration system" in Japanese clinical trials

CopperKettleQuote from a Japanese clinical trial report: METHOD: An observational study was conducted on patients who relapsed after primary systemic therapy with TZM using the central registration system. The primary end point was progression-free survival (PFS). Secondary end points consisted of the re...

 
7:24 AM
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Q: Crystacell supplement how does it help

Victor..this packet consists of 14sachets and from Malaysia. How can l get it as from its country. What help does it offer?

 
 
5 hours later…
12:13 PM
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Q: Can a clinical trial involve patients not registered for it? A quote from a publication

CopperKettleQuote from a clinical trial report: The primary end point in this study was progression-free survival (PFS). This refers to the interval from the first day of trastuzumab administration for recurrence until the confirmation of disease progression. In all registered patients, the earliest appe...

 
 
1 hour later…
1:17 PM
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Q: How can one summarize categorical variables with frequency variables in a clinical study?

CopperKettleQuote: All eligible patients were analyzed. For the background of the patient population, categorical variables were summarized with the frequency and rate and continuous variables with fundamental statistics. The PFS and OS were estimated using the Kaplan-Meier method. Similarly, the PFS was...

 
 
1 hour later…
2:21 PM
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Q: Meaning of "histologically invasive diameter"

CopperKettleQuote: A total of 34 patients were registered between July 2009 and June 2012. The mean age was 53.5 years. The median follow-up time was 23.7 months (2-24 months). The age at the time of recurrence, state of menopause, T and N stage, histologically invasive diameter, number of lymph node met...

 
 
3 hours later…
5:34 PM
0
Q: What is the best book to learn about medicine in medieval times? (research for a novel)

souzanI am writing a novel where the main character is a healer in medieval times / a low-technology environment. Most of his work would involve field medicine, or treating people generally as a village healer. I don't know anything about medicine myself, so what is the best source for me to learn abo...

0
Q: Meaning of "Chest wall, Sp, Ps" in a description of tumor recurrence locations

CopperKettleFrom a clinical trial report: I think that Ps stands for parasternal (nodes) but what could Sp mean? I haven't found a mention of "Ps" in the literature by googling for about 20 minutes.

 
6:06 PM
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Q: Where might "Counter side Ax" be located? (Description of tumor location)

CopperKettleFrom a clinical trial article: The table describes the locations in which breast cancer tumors recurred in patients. I think that Ax means "axillary" or "axilla", but I don't understand the whole phrase: "Counter side Ax". Where might this be?

 
6:54 PM
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Q: Looking forward to joining a law enforcement training

SherriVealI am looking forward to joining the Ontario law enforcement but I have not started my serious training yet. I am looking for guidance on how to apply for the officer's position. I am regular at the gym with an adequate body mass. I really need to work on my upper body strength especially my shoul...

 

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