Consider the following topology on $\Bbb{R}$: $U$ is open if and only if $\Bbb{R}-U$ is countable or all of $\Bbb{R}$. I claim that if $A$ is an uncountable set in $\Bbb{R}$, then its closure is $\Bbb{R}$ (i.e., it is dense). Recall that the closure of $A$ is the smallest closed set containing $A$, and that closed sets are formed by taking complements of open sets, which obviously makes proper closed subsets countable.
Clearly, then, there is no way a proper closed subset could contain $A$, since an uncountable set cannot be a subset of a countable set, Hence, the closed subset must not be …