The typical substrate for lipases are esters, such as triglycerides where fatty acids are linked to the glyerol through ester linkages. I'm interested in whether lipases (such as pancreatic lipase) can cleave fatty acids linked to proteins by amide linkages. In lipopeptides, fatty acids are often...

I’ve read that Grignard reagants react pretty quickly with alcohols and carboxylic acids to form their respective conjugate bases. I’ve also learned that Grignards can be used for the prepararion of alcohols and carboxylic acids too. How is it possible to perform these reactions if the reagant wo...