I want to compare the electron density on methyl group between tri‐tert‐butyl(methyl)azanium (1) and triisopropyl(methyl)azanium (2), i.e. essentially the inductive effects of $\ce{-\overset{+}{N}R3}$ groups. $$\underset{\large\textbf{1}}{\ce{Me-\overset{+}{N}(t-Bu)3}}\qquad\underset{\large\textb...

What happens to the amino group when amino acid is added to a near neutral solution? How does it come about gaining an extra proton? I understand what happen to the carboxyl group, since it is a strong acid it will dissociates quickly to donate a proton.

In the following reaction, is compound I formed by SN2 and compound II formed via SN1 after a carbocation rearrangement? Or is there some rearrangement I'm not aware of?