I read about frontier orbitals, namely HOMO, LUMO. But what's exactly HOMO/LUMO? I know HOMO stands for highest occupied molecular orbital and LUMO stands for lowest unoccupied molecular orbital.
But I am not getting which orbital is to be tagged as HOMO, and which as LUMO. Consider the example ...
Gefitinib has been shown to be an effective tyrosine kinase inhibitor in a fraction (~$10$%) of non-small cell lung cancer patients.
These patients are characterized as having a mutation (usually a deletion or missense) in the EGFR gene affecting the ATP-binding site.
I have two questions:
-- ...
Gefitinib has been shown to be an effective tyrosine kinase inhibitor in a fraction (~$10$%) of non-small cell lung cancer patients.
These patients are characterized as having a mutation (usually a deletion or missense) in the EGFR gene affecting the ATP-binding site.
I have two questions:
-- ...
The Periodic Table
The Periodic Table