4:53 PM
@Pythoniscool for what it's worth I've never heard of any motherboard with compatibility issues. There may be some, but it will be rare and I would be shocked if an ASUS board was one of them, ASUS is a very mainstream company.
As a general rule, you only need to seriously worry if your hardware is non-standard. So you could have trouble getting Linux to work with say an external wireless card if those are still around. But I've never heard of issues with basic components like CPUs or motherboards. Some graphics cards, yes, but again that's gotten much better.
It would be very hard to manage to build your own desktop machine that would have problems with Linux.