Is it possible to do a Structure Activity Relationship for caffeine given that its structure is similar to that of adenosine? Maybe more potent analogues can be made using caffeine as lead compound? What could I do to conduct an in-silico study, say I make a new molecule (modified caffeine), in t...

The following general reaction proceeds with decrease in amount of substance, so increasing pressure should shift the position of equilibrium to the right. $$\ce{2 A(g) <=> B(g)}$$ But let's say the forward reaction is endothermic, and both $\ce{A}$ and $\ce{B}$ are gases. This means if the posit...