How do I ask and answer homework questions? and Open letter to students with homework problems — Ocaso Protal 18 secs ago

The question is too broad for SO. Better suited for softwareengineering.stackexchange.com, probably too broad too. Some server frameworks may have better capabilities for integrating client frameworks but not django+vue afaik. So it's either python ssr + vue csr for dynamic widgets that aren't important for seo. Or python rest + vue ssr for better seo and ux. "Would I need DRF then as well?" - probably no, but this depends on your case, as well as other things — Estus Flask 52 secs ago

If this is on-topic anywhere on Stack Exchange, it might be Software Engineering, but I'd need to spend some time on Software Engineering Meta to evaluate whether it would in fact be within their rules either. — Charles Duffy 15 secs ago