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3:29 PM
Good evening!
> Host cell protein content was evaluated using a commercially available culture of Chinese hamster ovary (CHO) cells.
Does the quote above make any sense, providing that the text describes the production of a drug in an E. coli strain -- not in a CHO strain?
I don't understand how does one asssess HCP content using a CHO culture if the producer strain is E. coli
Would this make a good question for the Bio SE?
I tried googling, but to no avail.
Maybe the authors meant to say that they validated their HCP evaluation procedure using a CHO culture, but they do not say that outright.
 

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