He claimed to find the atmosphere vital and creatively invigorating. Perhaps there was something to this: he had taken his languishing novel out of the trunk for the first time in nearly a year.
It by Stephen King
Could you guys tell what he meant by saying that the novel got taken out of the t...
The pandemic is not over until the fat lady sings.
> - Honey, do you know a three letter word for ‘eggs’? - It’s ova. - Why? Just because I’m terrible at crosswords?
I don't get this one:
> If a Lama with one L is a holy man in Tibet... And a Llama with two L's is an adorable beast of burden... What's a three L Lama? A big fire in Boston.
Unlike other flightless birds, the ratites have no keel on their sternum — hence the name, from the Latin ratis ('raft', a vessel which has no keel — in contradistinction to extant flighted birds with a keel).
Etymology of the day: zenana - the woman's part of the house -- From Hindi ज़नाना (zanānā), Urdu زنانه (zanānah), from Persian زنانه (zanâne, “womanly”), from زن (zan, “woman”). Related to Old English cwene (“woman”). More at quean.
> . In the move from roving to stationary bandits, Olson sees the seeds of civilization, paving the way, eventually for democracy, which by giving power to those who align with the wishes of the population, improves incentives for good government.
One-alarm fires, two-alarm fires, three-alarm fires, etc., are categories classifying the seriousness of fires, commonly used in the United States and in Canada, particularly indicating the level of response by local authorities. The term multiple-alarm is a quick way of indicating that a fire is severe and is difficult to contain. This system of classification is used by both fire departments and news agencies.The most widely used formula for multi-alarm designation is based on the number of units, (for example firetrucks, tankers, rescue vehicles and command vehicles) and firefighters responding...
> This political intervention culminated when the George W. Bush administration altered the National Cancer Institute website to suggest that abortion might cause breast cancer.
I never knew that there was a hypothesis that abortion increases the risk of cancer.
A woman in Moscow has just written on a forum that "I've decided to bear a child at 48 yo, because my physician said to me: another abortion, and you'll be getting cancer".
So I went and googled.
I am not shocked, because on 23 Feb 2022 a general practitioner told me that I was wrong to allow myself to be vaccinated against COVID.
For breast cancer, you could make the general assumption that progesterone is a bit preventive, compared to estrogen, and the longer a woman remains pregnant, the more progesterone there will be.
@alphabet I think she must be not be talking about normally-connected telephones that plug directly into the phone network using wires, but about those expensive new-fangled tiny little hand-held cordless computers people sometimes make choppy, low-audio-quality wireless calls with if they are near enough to a cellular tower as though it were a walkie-talkie not a telephone.
You know, the kind you can take anywhere but which break when you drop them on the road or in a puddle and which make such poor doorstops once they've hit their planned fashionably-obsolescent dates that they've spawned their own recycling centers and pawn shops and criminal networks. 😈
I've seen the phrase Solvitas perambulum translated in many places as "Solve it while you walk." But I don't understand the grammar, and I find myself doubting that it's really Latin.
Here are my thoughts so far. Solvitas sounds like an abstract noun, meaning something like "being-solved-ness". B...
Because it can present as depression/anxiety and yet be overlooked because there's no clear-cut anemia present.
> According to the WHO, about one-third of non-pregnant women suffer from anemia worldwide and 40% of pregnant women [4]. In about 50% of cases, this is due to severe ID.
This is a bit suspect. Maybe they mean "at least once in the course of their lives"?
Hard to imagine every third woman right now suffering from anemia.
> Fe2+ and tetrahydrobiopterin (BH4) are obligatory cofactors for the aromatic acid hydroxylases.
> Of note that, in the CNS, there is a positive feedback loop between serotonin anabolism and its capacity to stimulate iron encephalic entry, connecting serotoninergic transmission to iron transport.
So... would a person taking an SSRI antidepressant for 30 years get neurodegeneration with basal ganglia iron accumulation?
Neurodegeneration with brain iron accumulation is a heterogenous group of inherited neurodegenerative diseases, still under research, in which iron accumulates in the basal ganglia, either resulting in progressive dystonia, Parkinsonism, spasticity, optic atrophy, retinal degeneration, neuropsychiatric, or diverse neurologic abnormalities.
Some of the NBIA disorders have also been associated with several genes in synapse and lipid metabolism related pathways. NBIA is not one disease but an entire group of disorders, characterized by an accumulation of brain iron, sometimes in the presence of axonal...
Imagine if millions of people across the globe start having psychosis and dementia because they've been taking SSRI antidepressants for the last 30 years (since they became widespread)
@alphabet Selective Serotonin Reuptake Inhibitor. There will be more serotonin in the synapses. The total amount of serotonin is actually probably reduced.
@CowperKettle nope. For iron toxicity the most important factor is TIBC. An entirely different beast, no correlation with Hgb levels
> The certitude of Death, which no reprieve Can put off long; and which, divinely tender, But waits the outstretched hand to promptly render That draught whose slumber nothing can bereave
@CowperKettle this iron is different from the one circulating in the blood. As I said yesterday, the body will put iron where it needs it. Only if you bleed regularly do you need to worry about iron (I.e. if you're a woman or have coagulation disorders)
@CowperKettle well the thing is the type of thought experiment you're trying is actually pretty applicable to calcium. Unlike iron, calcium is constantly needed everywhere, and for many many purposes
In keratoconus, iron accumulates in the cornea, creating a ring of rust. Incidentally, in keratoconus, blood levels of lactoferrine are significantly decreased.
@CowperKettle and more importantly because it's lower than the threshold for hepatocellular injury. It could even be because of the season. Because of the weather! Who knows
> In large Russian cities, the share of unsold new apartments has increased. According to analysts, in Krasnodar, 83% of square meters are empty in new buildings, in Omsk - 80%, in Chelyabinsk - 74%, in Kazan and Krasnoyarsk - 73%, in Samara - 71%, in Novosibirsk, Rostov-on-Don and Volgograd - 69%, in St. Petersburg, Yekaterinburg, Ufa, Voronezh, Perm and Nizhny Novgorod - 60-67%, in Moscow - 57%.
@alphabet And B12 deficiency
In Moscow, some 80 000 newly-built apartments remain empty because of the lack of demand.
Dallol (Amharic: ዳሎል) is a locality in the Dallol woreda of northern Ethiopia. Located in Kilbet Rasu, Afar Region in the Afar Depression, it has a latitude and longitude of 14°14′19″N 40°17′38″E with an elevation of about 130 metres (430 ft) below sea level. The Central Statistical Agency has not published an estimate for the 2005 population of the village, which has been described as a ghost town.
Dallol currently holds the official record for record high average temperature for an inhabited location on Earth, and an average annual temperature of 35 °C (95 °F) was recorded between 1960 and 1966...
@tchrist I just saw somewhere that there are so many of these phones dropped in water in (presumably concentrated) areas that it is becoming worthwhile to harvest them for metals.
> In the late 19th century, a tongue-in-cheek tradition arose among American students of Greek who were all too familiar with Xenophon's usage of this vocabulary item: March 4 (a date phonetically similar to the phrase "march forth") became known as "Exelauno Day".
@jlliagre I need to have more discipline. Too often I focus on one word without taking in the whole board.
Have you ever stopped to consider that neige, genie, and eigen are anagrams of each other? I'm sure this must mean something, but I can't imagine what just yet.