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12:00 AM
@alphabet Thankfully, not rushes yet! Wow, 300 mg must be enough even for seizures!
@CowperKettle That's actually pretty normal for epilepsy
(At least for the extended-release formulation.)
I once tried carbamazepine up to the maximum dose, but felt absolutely nothing, and titrated it back slowly
I only held at the max dose for a week though.
I don't know whether to take part in the ParkRun today, at minus 26°C
12:46 AM
@Mitch Don't get caught???
In all seriousness, here's what I wrote a number of years ago on the subject: ell.meta.stackexchange.com/a/4867/41273
@Mitch I would describe myself as pretty dupe-happy, though I get where you're coming from. I will ignore a duplicate (or link it in the comments only) if the answers to it are terrible
Poem of the Day: To my Thoughts, by Taras Shevchenko, 1840, turned into a song
«Думи мої, думи мої» — вірш Тараса Шевченка, написаний 1840 року, ліричний вступ до «Кобзаря», літературний маніфест молодого автора, який представляє загалові свою першу книжку, а з нею — свій голос як національного поета України. == Історія написання та публікації == Вірш датується орієнтовно за часом підготовки рукопису «Кобзаря» 1840 року та подання його до цензури: січень — початок березня 1840 року, С.-Петербург. Автограф не відомий. Написаний, очевидно, пізніше від інших творів, що увійшли до «Кобзаря» 1840 року, рукопис якого подано до Петербурзького цензурного комітету 7 березня 1840 року...
2 hours later…
2:42 AM
Word of the day: hoodoo (Hoodoos typically consist of relatively soft rock topped by harder, less easily eroded stone that protects each column from the elements. They generally form within sedimentary rock and volcanic rock formations.)
Is that the scientific name?
hoodoo n 1 a. Magic healing and control, especially in African-based folk medicine in the United States and the Caribbean ... v 1. To practice hoodoo on; affect with a charm or curse.
3:00 AM
@Cerberus Wikipedia says so, thus it's true.
A hoodoo (also called a tent rock, fairy chimney, or earth pyramid) is a tall, thin spire of rock formed by erosion. Hoodoos typically consist of relatively soft rock topped by harder, less easily eroded stone that protects each column from the elements. They generally form within sedimentary rock and volcanic rock formations. Hoodoos range in size from the height of an average human to heights exceeding a 10-story building. Hoodoo shapes are affected by the erosional patterns of alternating hard and softer rock layers. Minerals deposited within different rock types can cause hoodoos to hav...
It sounds like a word someone invented who didn't know what they were called, the things, those what do you call them, those hoodoos?
4:02 AM
> The name is derived from Hoodoo spirituality, in which certain natural forms are said to possess certain powers, but by the late 19th century, this spirituality became associated with bad luck.
Hoodoo is a set of spiritual practices, traditions, and beliefs that were created by enslaved African Americans in the Southern United States from various traditional African spiritualities, Christianity and elements of indigenous botanical knowledge. Practitioners of Hoodoo are called rootworkers, conjure doctors, conjure man or conjure woman, and root doctors. Regional synonyms for Hoodoo include rootwork and conjure. As a syncretic spiritual system, it also incorporates beliefs from Islam brought over by enslaved West African Muslims, and Spiritualism. Scholars define Hoodoo as a folk religion...
4:42 AM
Q: Thank you, Professor Lawler and Rest in Peace!

LaurelI am saddened to announce the passing of John Lawler on Saturday November 25. Many of us here were friends with him, and countless more helped by his answers. For those of you who aren't familiar with him, a short biography: In 2009, John retired from the Linguistics Department at the University ...

1 hour later…
5:49 AM
Congo Square (French: Place Congo) is an open space, now within Louis Armstrong Park, which is located in the Tremé neighborhood of New Orleans, Louisiana, just across Rampart Street north of the French Quarter. The square is famous for its influence on the history of African American music, especially jazz. == History == In Louisiana's French and Spanish colonial era of the 18th century, enslaved Africans were commonly allowed Sundays off from their work. Although Code Noir was implemented in 1724, giving enslaved Africans the day off on Sundays, there were no laws in place giving them the right...
Now I understand the name of a Ukrainian rock band.
> TNMK, a Ukrainian band from Kharkiv, is named after the square; their name is an abbreviation of the Ukrainian translation of "Dance At Congo Square".
I never mused about the name, since band often have nonsensical names.
2 hours later…
8:08 AM
Wordle 903 4/6

1 hour later…
9:21 AM
Looks like it's too dangerous to run in temperatures below minus 15C, because your lung tissue undergoes non-reversible remodeling ualberta.ca/folio/2020/01/…
I never knew that.
A good bit of info to pass on.
10:06 AM
La Madonna del manganello (in Calabria nota come Madonna della mazza) è una rappresentazione iconografica della figura cristiana della Madonna, diffusasi inizialmente a Monteleone (la futura Vibo Valentia) e a Nicastro (oggi quartiere di Lamezia Terme) durante il ventennio fascista e caduta in disuso con la fine del regime. Una statua con tale rappresentazione, da cui vennero tratti dei santini, era presente a Monteleone, ma scomparve alla fine della seconda guerra mondiale. == Iconografia == La Madonna del manganello, che mai ricevette un riconoscimento ecclesiastico ufficiale, rientrò i...
Madonna with a baseball bat.
10:48 AM
#Worldle #687 1/6 (100%)
@CowperKettle Batwoman!
#Worldle #687 1/6 (100%)
11:26 AM
What kinds of edible mushrooms are prominent in western countries? I presume shiitake, enoki, and heimuer aren't common there?
Boletus is a genus of mushroom-producing fungi, comprising over 100 species. The genus Boletus was originally broadly defined and described by Carl Linnaeus in 1753, essentially containing all fungi with hymenial pores instead of gills. Since then, other genera have been defined gradually, such as Tylopilus by Petter Adolf Karsten in 1881, and old names such as Leccinum have been resurrected or redefined. Some mushrooms listed in older books as members of the genus have now been placed in separate genera. These include such as Boletus scaber, now Leccinum scabrum, Tylopilus felleus, Chalciporus...
Boletus edulis (English: cep, penny bun, porcino or porcini) is a basidiomycete fungus, and the type species of the genus Boletus. Widely distributed in the Northern Hemisphere across Europe, Asia, and North America, it does not occur naturally in the Southern Hemisphere, although it has been introduced to southern Africa, Australia, New Zealand, and Brazil. Several closely related European mushrooms formerly thought to be varieties or forms of B. edulis have been shown using molecular phylogenetic analysis to be distinct species, and others previously classed as separate species are conspecific...
There's lots of edible mushrooms here.
Never heard of them; interesting.
It's considered the best kind of mushroom here in Russia.
A children's song in Ukrainian about edible mushrooms.
In the song, the merry mushroom family proceeds to.. eat mushrooms.
@jlliagre It was the Fascist Madonna, popular among them during the "Twenty Years" - the period when Italy was ruled by Fascists. Because they loved to beat up their opponents with clubs (manganello) in the streets.
12:09 PM
@CowperKettle Why bother with cultural details, let's just enjoy the puns! ;-)
12:35 PM
@DannyuNDos Shiitake mushrooms are quite common, but I've never heard of the other two.
"Button mushrooms" are so common that they're often just referred to as "mushrooms."
I'm looking for mushrooms that have Vitamin D but I can't find any of them on Amazon. I looked a few but none of them mention Vitamin D.
I have read that dried mushrooms have vitamin D
I read an article which says Shiitake mushrooms have vitamin D.
2 hours later…
2:16 PM
@jlliagre They are interesting! I was just feeling overloaded yesterday.. but I felt that I should somehow reply. I'm not against cultural details!
@Vikas Maybe it's easier just to buy Vitamin D supplements :)
I take 25 000 IU each Saturday.
@alphabet Ah. We call them champingons
2:40 PM
@CowperKettle I know. Enjoy both!
#Worldle #687 1/6 (100%)
2:59 PM
@CowperKettle When I used to run in extreme winter temps I would wrap a scarf around my neck and lower head, and breathe through it during the run. No problem with the breathing, but it often left a crust of ice on the front of the scarf!
@Vikas The "Nutrition Facts" on American food labels never mention Vitamin D, I think.
The worst part about running on sidewalks in the city during the winter was the patches of ice you would encounter. Suddenly feeling your foot slip to the side could make you pull a muscle, especially a groin muscle.
That was the dangerous part, because a groin pull could be problematic for six months.
@Robusto I guess same reason could be here too. On one more popular Indian grocer site, the nutrition table doesn't mention any vitamins, but interestingly, in the title they do mention "Rich in vitamin D".
But I won't believe it they are right about it. They have even made typo in "shitake' lol
3:18 PM
The shiitake (alternate form shitake) (; Japanese: [ɕiꜜːtake] Lentinula edodes) is an edible mushroom native to East Asia, which is cultivated and consumed around the globe. It is considered a medicinal mushroom in some forms of traditional medicine. == Taxonomy == The fungus was first described scientifically as Agaricus edodes by Miles Joseph Berkeley in 1877. It was placed in the genus Lentinula by David Pegler in 1976. The fungus has acquired an extensive synonymy in its taxonomic history: Agaricus edodes Berk. (1878) Armillaria edodes (Berk.) Sacc. (1887) Mastoleucomychelloes edodes (Berk...
This lists the Vitamin D for a single serving as "3%" of daily requirements. So not exactly "rich" in that vitamin.
@Vikas Congrats for noticing! Many people wouldn't.
@CowperKettle But for that I will need to go to doctor first? Also there seems to be many kinds of D (D2, D3 K2) etc. seems overwhelming. So I'm just looking for at least one natural food which contains vitamin D.
In hiragana, it's spelled しいたけ (shi i ta ke, four syllables).
Also I remember during childhood my father would sometimes bring some "iron" tablets from his goverment school for me. They were provided for free for kids in school. Some red colored tablets.
> Like all mushrooms, shiitakes produce vitamin D2 upon exposure of their internal ergosterol to ultraviolet B (UVB) rays from sunlight or broadband UVB fluorescent tubes.[20][21]
Used to look like these.
They wouldn't taste bitter like other medicines but had a horrible taste.
@Robusto Yeah so it must be dried in sun. That is also problem. I can't be sure if they have actually dried in the sun properly.
@Robusto That is also true. Insufficient.
3:28 PM
Where you are you should get enough Vitamin D from sunlight exposure.
@Robusto I was coming to that:
> From October to March our bodies can’t make enough vitamin D from sunlight.

So to keep bones and muscles healthy, it’s best to take a 10 microgram supplement of vitamin D. You can get vitamin D from most pharmacies and retailers.

Find out more by searching 'Vitamin D' on the NHS website.
I'm not sure if it's true for India as well?
I don't know. What's the sunlight like in the winter there?
Otherwise I can spend enough time in sun at least during next three months.
@Vikas No, I don't think that it's necessary to go to a doctor for vitamin D. It's freely sold everywhere. The main thing is not to get an overdose, but it's hard to get overdosed.
One can take up to 4000 IU every day without the risk of overdose.
So I'm taking 3000+ IU
@Robusto I don't know how much sunlight they would consider good or bad. If it's not cloudy weather and no fog, there is sunlight. It's not harsh like summer. It's very comfortable and makes me keep sitting there whole day.
3:32 PM
Sounds like you should get enough then.
But if you have free healthcare, or the money for a doctor, it's totally okay to go to a doctor and ask him to check your vitamin D levels and the levels of associated parameters. Calcium, parathyroid hormone, etc. Whatever the doctor feels necessary.
@CowperKettle Also I think it's a good idea to first actually check how much I'm deficient in D. With the help of doctor and tests.
@Vikas Yes, it could be.
@CowperKettle Yeah that is what I am thinking.
I was amazed to have a level of 19 ng/mL after spending the whole summer bicycling and running.
I then started on 1000 IU of vitamin D per day, and two months later... I had a level of 17 ng/mL.
3:34 PM
@CowperKettle What level is considered healthy?
@Robusto From 30 to about 60 ng/ml
But in reality, I think levels from 20 ng/ml and higher are okay.
There is no universal opinion.
Below 20 ng/ml is slightly deficient, and below 10 ng/ml your parathyroid hormone will go out of kilter. Below 10 it's the rickets zone
Haha. I guess you have to really stay in the sun. Which is not good for your skin.
Yes, or maybe I have something wrong with my metabolism.
@Robusto My father and two of his friends were chatting for at least three hours today in the sun.
It wasn't continuous though.
If you spend too much time you start to feel lazy and sleepy.
3:40 PM
@Vikas Not me. I commonly cycle in the sun for three or more hours in the summer. But I'm slathered with sunscreen during that time, so I'm not really sure how much Vitamin D exposure I get.
@CowperKettle Wait, did it reduce after taking supplement?
@Robusto I agree during riding or bicycling experience is different.
@jlliagre Looks like someone changed this meme format from sketch to 3D render.
I mostly saw it as a pencil sketch format.
@Vikas Yes, there is a vague resemblance ;-)
3:57 PM
Jun 19, 2022 at 14:28, by Vikas
I sat near a baby Neem tree today.
I think I'll need to correct myself about this old post.
IIRC it's the same tree after more than a year.
But it's the Melia azedarach tree.
It's not Neem. It looks similar to Neem though. Especially when it was small.
Melia azedarach and Azadirachta indica (Neem) belong to same family "Meliaceae". I guess that's why they look similar.
@Vikas Yes, it reduced, because it was October or November, and my levels slightly declined even despite 1000 IU of vitamin D per day
@CowperKettle Ah
Because there's not a lot of sunshine here in November
@Vikas Beautiful view!
@CowperKettle minus some pollution.
I could walk 2.5 miles today without much issue so I guess pollution level is going down.
This is good!
I've run some 10 km today
At some points during the run, I stopped feeling some of my fingers. Because I was fiddling with the mp3 player to switch to a different song, and took off the gloves for about 10 seconds.
4:06 PM
That is double of your recent runs.
Yes, because it takes 3 km to reach the center of the city, where the Saturday ParkRun takes place :)
I will walk 10 Kms some day just to see what happens. But I guess that will take me 2 to 3 hours with my usual speed.
I wore two balaclavas, one atop another, and on top of that, a hat.
For 4 Kms it takes me around 40 minutes.
@CowperKettle Do you run with a group?
The player's headphone wires became rigid from the cold
4:09 PM
@Vikas In my 20s I used to do 8 km (5 miles) in 35 minutes before breakfast. Those days are gone.
@Vikas Yes, the so-called 5Verst (5Верст) run, every Saturday
@Robusto And my 20s are also gone :(
In my 10s, I used to hate running.
I was very active in childhood.
@CowperKettle The maximum run I did was in college play ground. I had a friend he would run daily in evening. Basically you run around the square play ground completing laps. Once he told me he can take around 10 laps. One lap was around 400 meters.
So one day I decided to break his record. I took around 13 laps.
And for next 30 minutes I kept sitting on ground feeling like heaven.
I wasn't able to walk but I felt so good.
After that I made a habit to run daily a few laps.
At ages 14 and 15 I sometimes ran to the lake with a friend, then we chatted on the lake shore, then ran back.
It felt like a big distance, but it's only 3 kilometers.
4:17 PM
@CowperKettle Yeah childhood distances appear to be much smaller when we grow up.
I used to think my school playground was huge. If I go today, it looks so small.
Just over 3 km.
They've installed some cute bus stop near the lake
And matryoshka dolls along the road
Looks nice
A road made out of prestressed concrete slabs designed and used for construction of 5-storey house blocks
It must quite expensive.
These roads were everywhere in the North
4:26 PM
Looks well made.
Our apartment block's doors opened to driveways made out of such slabs.
Title levels are aligned.
Only in the 1980s, the builders had forgot to remove some of the thick steel eyelets intended for lifting the slabs. So there were these mangled eyelets sticking out.
Me and other small boy played boxing, and I fell and hit my forehead on such half-broken eyelet.
Had a concussion, spent a week in bed.
We have some concrete/cement roads as well.
Up to age 12 or 13 there was a visible scar on my forehead.
Like Harry Potter's
4:30 PM
You're a wizard!
Yes. Later I learned that it's very bad to have your head hit like that in childhood.
Even professional boxers have lowered IQ scores and some pathology, being unable to control themselves, from hits to their heads
Yes, concrete roads are used everywhere: housing.com/news/concrete-roads
@CowperKettle I have a similar memory where my cousin fell on this kind of lever on a tractor. She was on the tractor and fell down. There was blood on her forhead. I can't remember fully. Probably a doctor came and treated her.
She was probably 5 years old only.
@Vikas My mother laid me on the bed, and ran out to get a doctor. I sat up in bed, and took a book and tried to read (or look at the pictures). When she returned, the book was messed up with blood dripping from my forehead.
She was not impressed.
@CowperKettle You still wanted to read 🤣
Yes.. I was obsessed with books
4:39 PM
Not a bad obsession at all.
I used to read a couple hours just to be able to fall asleep
My father collected books. It was hard to buy good books in the Soviet times, so he made presents to ladies working in book stores. When a good book arrived, they would hide one, to sell to him later. Because all very interesting books were sold out in a moment.
It was easy to buy some boring Communist books, and very hard to buy books by foreign authors.
Once he grew a lemon tree in our apartment, and it grew quite high, so we gifted it to a bookstore.
Grew in a pot?
5:18 PM
> Again, I make this point — are we seriously arguing that the authors of the amendment wrote it so Jefferson Davis couldn't be a congressman from Mississippi but that he could be elected president? Yes, in fact, we are arguing that very thing.
@tchrist ^
@Robusto It's easy, perhaps too easy, to fantasize that they're deliberately providing an opinion so ridiculous as to provoke correction from SCOTUS. But I am no court watcher.
@Robusto The lab that does my bloodwork considers the normal range for vitamin D to be between 30.0 and 100.0 ng/mL. I came in at 24.7 a couple weeks ago, which to that lab is a little low.
@tchrist I wonder if the blood tests I get check for that.
@Robusto It really depends on how extensive the tests your PCP orders done for an annual physical, or sometimes in prep for other treatments, procedures, or diagnoses. I had to specifically request that he include that one.
5:34 PM
@tchrist Hmm, mine came in at 27. A bit low, but I suppose survivable.
Mine posits 30-100 as the "normal" range.
Yes, that's what mine does as well.
My doc still recommended 2,500 IU daily.
I'm not sure that the 1,000 IU daily that @CowperKettle was prescribed for numbers below 20 were enough to move the dial.
@tchrist The problem with megadoses of D is that you can develop kidney stones. Which are not fun, as I've found. For a while I had to take 50,000 IU a week, on doctor's orders, and I developed those.
Holy cow.
5:40 PM
They didn't develop until some months later.
> If the amount in your blood is below 20 ng/mL, your levels are inadequate; if it's below 12 ng/mL, that means you're deficient in the nutrient. If that's the case, your doctor may prescribe a megadose of 50,000 IUs to take once a week for six to 12 weeks to raise the level of vitamin D circulating in your body.
Or else they didn't ripen till then.
@tchrist Yup.
When you had the stones, was your kidney function normal?
Well, except for that small fact.
> I don't want any of these people — let alone the Republican frontrunner — within a country hectare of the White House, but Ramaswamy is a whole 'nother thing entirely.
Like so many rats all climbing atop one another in a scramble for meaningless crumbs of nothingness.
5:50 PM
Yes. This all would be laughable except that it's so tragic.
In a country where you're frequently forbidden from teaching the true cause and consequences of its own civil war, there is no hope that civics lessons teach the many grim historical accounts of past republics willingly handing over power to brutal dictatorships.
I've decided to call this primary "the race for second place." As with the 2016 primary, people just ignore the polls and pretend someone other than Cinnamon Man might win.
The news media, of course, hypes up the debates, because an uncompetitive race is boring for the press. But people ought to prepare for the most likely outcome.
I suspect that attempts to jail him or bar him from running will backfire massively, making him seem like a martyr or political prisoner.
Time to pretend we like Joe Biden again.
6:19 PM
@tchrist Yes, including forcing women to play Russian Roulette with pregnancy.
@tchrist in most cases it is. Just hurts like hell
@tchrist raising vit D levels beyond 50 ng/mL is probably not good. Doubleplusungood, actually. But more studies are needed.
@Robusto there is a possible link with high vit D and the risk of pancreatic cancer, for instance. But as I said, it's far from proven.
@Robusto routine tests don't, my nephrologist remembers to order it once a year.
Which is quite a feat. I won't remember my name by that age.
@M.A.R. Sometimes it seems like medicine takes a Whack-A-Mole approach to health. Solve one problem, cause another.
@Robusto Drugs are just poisons with acceptable safety margins.
Sometimes unacceptable, e.g. digoxin, warfarin
I can't recall anyone ever giving me a warning about drug interactions, either.
You haven't met many underworked energetic conscientious pharmacists such as myself obviously
Dear diary, today I lectured an idiot for 15 damn minutes on why self-medicating with antibiotics is a bad idea. And they didn't take my advice. The usual.
See, if that happens four times a day every winter season I'm not sure I'd remain energetic OR conscientious by the fifth year in a pharmacy
6:30 PM
@M.A.R. You don't need a prescription for those in your country?
@Robusto on paper only. In practice, people here think pharmacies are like supermarkets.
Prepping for the next epidemic, I guess.
It's . . . kinda complicated. It's cruel to tell an old fella with financial problems and knee osteoarthritis who wants some medication to be able to sleep to go fish.
@M.A.R. What kind of medicine?
Otherwise, unless every pharmacy decides to stop selling antibiotics without prescription, and such harmony would only come from a higher power, if someone can't buy it from me, they'll but it from the pharmacy two blocks over
@Robusto well, old people who are not freaking Tour de France champions tend to have a lot of anxiety due to other medications or psychiatric problems. Oxazepam is a good drug to recommend to them to relieve their anxiety to get a good night's sleep.
It's almost definitely Rx-only. Well, on paper. Because it's in the same family as Valium and Xanax
So I can't just tell him to get a prescription and a cursory lookup that will cost one fifth of his monthly income, just to have a doctor reach the same conclusion
6:40 PM
@M.A.R. Yeah. Benzodiazepines. Not good.
7:32 PM
@M.A.R. Here it's a controlled substance, making it somewhat annoying to fill prescriptions for. You can buy OTC sleep aids containing diphenhydramine or doxylamine, though.
@Robusto Clearly you aren't on enough medications.
That said, pharmacists here have little role in medical decision-making; they get a fair amount of training but mostly just end up doing the paperwork needed for dispensing medication.
Word I wish I hadn't learned of the day: selfcest. Defined by Wiktionary as "(fandom slang, fiction) Sexual activity with an alternate version of oneself, such as a clone, duplicate, alter ego, or a version of oneself from a different time or alternate universe."
2 hours later…
9:29 PM
@alphabet benzodiazepines help you sleep for a couple of weeks only. After that, GABA A receptors change enough that they're not really sleeping aids anymore, but their anticonvulsant, muscle relaxant and anxiolytic effects mostly remain
Benzodiazepine misuse is mostly caused by people trying ever higher doses of the drug due to their insomnia.
1 hour later…
10:46 PM
@M.A.R. The same happens with diphenhydramine, of course. I've had a couple of times I took it several nights in a row. Eventually it stopped working, and I didn't sleep well when I stopped taking it.
I have heard people say that the same thing occurs with effects of benzodiazepines on anxiety; here, at least, they're very strongly discouraged as treatments for anxiety disorder because of the risk of dependence (and addiction)
1 hour later…
11:54 PM
@Robusto I'm sorry to hear that!
I've read that one must really double down on vitamin D to get to a dangerous level
Yeah, vitamin D is lipophilic; it doesn't get urinated out easily.

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