@tush Depends on what you need to do with the data and where the device will be running and if it will be autonomous and all that

I'd use Python probably to run the sensor if it's autonomous and then process the data in Mathematica

Python has a smaller footprint, starts up quickly for cron jobs, has a permissive license, isn't going to try to authenticate against some server, etc.

Now if you want an interactive control panel for real time work, that I would maybe do in Mathematica